SCHEMBL7794933

SCHEMBL7794933

CCCCCC(C)(C)c1cc(CC(=O)O)ccc1OC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.52
ALDH1A1 P00352 3/20 0.49
TSHR P16473 1/20 0.49
NFKB1 P19838 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
CA5A P35218 1/20 0.47
PTPN11 Q06124 2/20 0.44
PTPN1 P18031 1/20 0.44
PTPN6 P29350 1/20 0.44
HPGD P15428 1/20 0.43
HSD17B10 Q99714 1/20 0.43
PPARG P37231 1/20 0.43
PPARA Q07869 1/20 0.43
CNR1 P21554 1/20 0.43
CNR2 P34972 1/20 0.43
PTGS1 P23219 1/20 0.43
AKR1C3 P42330 1/20 0.43
AKR1C2 P52895 1/20 0.43
NPSR1 Q6W5P4 1/20 0.42
NR1H4 Q96RI1 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7792674 0.88 LTA4H (0.47) PPARGPPARA
SCHEMBL7796102 0.85 GAA (0.59) GAAALDH1A1TSHRNFKB1TDP1
SCHEMBL7794931 0.84 GAA (0.57) GAAALDH1A1TSHRNFKB1TDP1
SCHEMBL7796464 0.83 ALDH1A1 (0.49) GAAALDH1A1TSHRNFKB1TDP1
SCHEMBL7792653 0.82 TSHR (0.50) ALDH1A1TSHRPTPN11HPGDCNR1
SCHEMBL6567363 0.82 CNR2 (0.44) PPARGPPARACNR1CNR2
SCHEMBL7796119 0.81 GAA (0.64) GAAALDH1A1TSHRNFKB1TDP1
SCHEMBL8090921 0.81 PLA2G4B (0.51) ALDH1A1TSHRPTPN11HPGDCNR1
SCHEMBL6567744 0.81 PPARG (0.44) PPARGPPARACNR1CNR2
SCHEMBL9132226 0.81 PLA2G4B (0.51) ALDH1A1TSHRPTPN11HPGDCNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0823435-B1 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL CO (JP) 2001-11-21 EP disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5889095-A OXYGEN AND HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-03-30 US disclosed
EP-0823435-A2 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-11 EP disclosed