SCHEMBL7792674

SCHEMBL7792674

CCCCCC(C)(C)c1cc(CCC(=O)O)ccc1OC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 4/20 0.47
CYP3A4 P08684 4/20 0.47
CYP1A2 P05177 3/20 0.47
CYP2C8 P10632 3/20 0.47
CYP2C9 P11712 3/20 0.47
CYP2B6 P20813 3/20 0.47
CYP2C19 P33261 3/20 0.47
PPARA Q07869 3/20 0.47
PPARG P37231 1/20 0.47
HTR1A P08908 3/20 0.44
TRPV1 Q8NER1 2/20 0.44
CYP2E1 P05181 1/20 0.44
ALOX5 P09917 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2A6 P11509 1/20 0.44
FFAR1 O14842 2/20 0.44
FFAR4 Q5NUL3 2/20 0.44
TLR7 Q9NYK1 1/20 0.43
FFAR2 O15552 1/20 0.43
PPARD Q03181 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7794933 0.88 GAA (0.52) PPARAPPARG
SCHEMBL7794917 0.86 FFAR1 (0.48) PPARAALOX5FFAR1FFAR4FFAR2
SCHEMBL6567363 0.85 CNR2 (0.44) LTA4HCYP3A4CYP1A2CYP2C8CYP2C9
SCHEMBL7792671 0.85 FFAR1 (0.47) PPARAPPARGALOX5FFAR1FFAR4
SCHEMBL7942317 0.84 LTA4H (0.43) LTA4HCYP3A4CYP1A2CYP2C8CYP2C9
SCHEMBL6567744 0.84 PPARG (0.44) LTA4HCYP3A4CYP1A2CYP2C8CYP2C9
SCHEMBL7786554 0.84 IAPP (0.48) LTA4HCYP3A4CYP1A2CYP2C8CYP2C9
SCHEMBL7792665 0.82 FFAR1 (0.51) PPARAALOX5FFAR1FFAR4FFAR2
SCHEMBL7796629 0.81 THRA (0.46) FFAR1FFAR4
SCHEMBL7792653 0.80 TSHR (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0823435-B1 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL CO (JP) 2001-11-21 EP disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
EP-0823435-A2 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-11 EP disclosed