Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7795164 | 0.92 | MEN1 (0.45) | TP53HPGDNPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7786850 | 0.88 | NPC1 (0.53) | TP53HPGDNPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7796798 | 0.88 | RARB (0.47) | TP53HPGDALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7786885 | 0.86 | CHEK1 (0.50) | TP53HPGDALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL9286338 | 0.82 | SMN1; SMN2 (0.47) | TP53HPGDNPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7786884 | 0.81 | RARA (0.49) | HPGDALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL8321300 | 0.81 | RARA (0.64) | TP53HPGDALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7792898 | 0.80 | PDE4A (0.53) | TP53HPGDNPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7796793 | 0.80 | RARB (0.47) | TP53HPGDALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7786848 | 0.80 | LMNA (0.50) | TP53HPGDNPC1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643701-B1 | BENZIMIDAZOLE-DERIVED COMPOUNDS, METHOD FOR PREPARING SAME, AND THERAPEUTICAL AND COSMETIC USES THEREOF | CT INTERNAT DE RECH S BR DERMA (FR) | 2001-12-05 | — | — | EP | claimed |
| US-5446059-A | Treating or preventing inflammatory or immunoallergic conditions | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1995-08-29 | — | — | US | claimed |
| EP-0643701-B1 | BENZIMIDAZOLE-DERIVED COMPOUNDS, METHOD FOR PREPARING SAME, AND THERAPEUTICAL AND COSMETIC USES THEREOF | CT INTERNAT DE RECH S BR DERMA (FR) | 2001-12-05 | — | — | EP | disclosed |
| US-5446059-A | Treating or preventing inflammatory or immunoallergic conditions | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1995-08-29 | — | — | US | disclosed |