Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | RARA | P10276 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RARG | P13631 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.43 |
| ▸ | IKBKB | O14920 | 2/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7796793 | 0.92 | RARB (0.47) | RARBKDM4EALDH1A1TP53HPGD | |
| SCHEMBL7786953 | 0.90 | AMY1A (0.50) | RARBKDM4EALDH1A1TP53HPGD | |
| SCHEMBL7795169 | 0.88 | TP53 (0.52) | RARBKDM4EALDH1A1TP53HPGD | |
| SCHEMBL7047540 | 0.85 | RARB (0.50) | RARBKDM4EALDH1A1TP53HPGD | |
| SCHEMBL7786948 | 0.83 | RARB (0.44) | RARBKDM4EALDH1A1TP53HPGD | |
| SCHEMBL7786885 | 0.82 | CHEK1 (0.50) | RARBKDM4EALDH1A1TP53HPGD | |
| SCHEMBL8321300 | 0.82 | RARA (0.64) | RARBKDM4EALDH1A1TP53HPGD | |
| SCHEMBL7795164 | 0.80 | MEN1 (0.45) | RARBKDM4EALDH1A1TP53HPGD | |
| SCHEMBL9286338 | 0.79 | SMN1; SMN2 (0.47) | RARBKDM4EALDH1A1TP53HPGD | |
| SCHEMBL7786850 | 0.77 | NPC1 (0.53) | RARBKDM4EALDH1A1TP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643701-B1 | BENZIMIDAZOLE-DERIVED COMPOUNDS, METHOD FOR PREPARING SAME, AND THERAPEUTICAL AND COSMETIC USES THEREOF | CT INTERNAT DE RECH S BR DERMA (FR) | 2001-12-05 | — | — | EP | claimed |
| US-5446059-A | Treating or preventing inflammatory or immunoallergic conditions | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1995-08-29 | — | — | US | claimed |
| EP-0643701-B1 | BENZIMIDAZOLE-DERIVED COMPOUNDS, METHOD FOR PREPARING SAME, AND THERAPEUTICAL AND COSMETIC USES THEREOF | CT INTERNAT DE RECH S BR DERMA (FR) | 2001-12-05 | — | — | EP | disclosed |
| US-5446059-A | Treating or preventing inflammatory or immunoallergic conditions | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1995-08-29 | — | — | US | disclosed |