Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 15/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7797212 | 0.83 | ALOX5 (0.43) | ALOX5NR1I2 | |
| SCHEMBL7799037 | 0.72 | ACE2 (0.33) | — | |
| SCHEMBL4193356 | 0.71 | AKT1 (0.60) | ALOX5PPARGPPARANR1I2AKT1 | |
| SCHEMBL6028036 | 0.70 | CYP3A4 (0.63) | ALOX5NR1I2 | |
| SCHEMBL5675007 | 0.70 | CYP3A4 (0.63) | ALOX5NR1I2 | |
| SCHEMBL5674832 | 0.70 | CYP3A4 (0.63) | ALOX5NR1I2 | |
| SCHEMBL4779257 | 0.70 | ALOX5 (0.51) | ALOX5PPARGPPARANR1I2 | |
| Ethane SCHEMBL4283975 | 0.69 | CYP3A4 (0.62) | ALOX5NR1I2 | |
| SCHEMBL8712759 | 0.69 | ALOX5 (0.33) | ALOX5NR1I2AKT1 | |
| SCHEMBL10346571 | 0.68 | PSEN1 (0.50) | ALOX5NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010012901-A1 | Sulphonyl compounds for use as linkers in solid phase and combinatorial synthesis | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2001-08-09 | — | — | US | disclosed |
| US-6225480-B1 | FOR SYNTHESIS OF ORGANIC COMPOUNDS CONTAINING--NH--GROUPS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010012901-A1 | Sulphonyl compounds for use as linkers in solid phase and combinatorial synthesis | H1-0, H1-2, ASH2L | ALOX5 2905/4885PPARG 4688/4885PPARA 4379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.