Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27685661 | 0.82 | GAA (0.66) | ALDH1A1TDP1MAPTGAATHRB | |
| SCHEMBL11633060 | 0.81 | TDP1 (0.54) | ALDH1A1TDP1MAPTGAAMEN1 | |
| SCHEMBL28343138 | 0.79 | ALDH1A1 (0.69) | ALDH1A1TDP1MAPTGAATHRB | |
| SCHEMBL7245897 | 0.79 | ALDH1A1 (0.65) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL27864754 | 0.78 | TDP1 (0.64) | ALDH1A1TDP1MAPTGAATHRB | |
| SCHEMBL15811368 | 0.78 | TDP1 (0.50) | ALDH1A1TDP1MAPTGAAMEN1 | |
| SCHEMBL14302439 | 0.78 | ALOX15 (0.51) | ALDH1A1TDP1MAPTGAATHRB | |
| SCHEMBL17263732 | 0.77 | ALDH1A1 (0.67) | ALDH1A1TDP1MAPTGAATHRB | |
| SCHEMBL17420851 | 0.77 | ALDH1A1 (0.61) | ALDH1A1TDP1MAPTGAAMEN1 | |
| SCHEMBL10712973 | 0.76 | ALDH1A1 (0.71) | ALDH1A1TDP1MAPTGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010004779-A1 | Novel p-aminophenol derivatives and the use thereof | ROSE DAVID (DE) | 2001-06-28 | — | — | US | disclosed |
| CN-1282317-A | Novel P-aminophenol derivatives and use thereof | HENKEL KGAA (DE) | 2001-01-31 | — | — | CN | disclosed |
| EP-1044185-A2 | NEW DERIVATIVES OF P-AMINOPHENOL AND THEIR USE | Henkel Kommanditgesellschaft auf Aktien (DE) | 2000-10-18 | — | — | EP | disclosed |
| WO-1999031054-A2 | NOVEL P-AMINOPHENOL DERIVATIVES AND THE USE THEREOF | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1999-06-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010004779-A1 | Novel p-aminophenol derivatives and the use thereof | KRT18, S100P, CKAP4 | ALDH1A1 1269/4885TDP1 2468/4885MAPT 369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.