Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 4/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.33 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.33 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7792456 | 0.86 | BACE1 (0.39) | KMT2A | |
| SCHEMBL7792324 | 0.84 | ALDH1A1 (0.38) | ACSS2ALDH1A1 | |
| SCHEMBL7792672 | 0.84 | KDM4E (0.32) | KDM4EMEN1KMT2AMAPTHPGD | |
| SCHEMBL7786096 | 0.83 | ACSS2 (0.35) | ACSS2KDM4EALDH1A1 | |
| SCHEMBL7792344 | 0.83 | PTGDR2 (0.43) | KDM4EHSD17B10KMT2AMAPTALDH1A1 | |
| SCHEMBL7792081 | 0.83 | PTGDR2 (0.43) | KDM4EHSD17B10KMT2AMAPTALDH1A1 | |
| SCHEMBL7796343 | 0.83 | PTGDR2 (0.43) | KDM4EHSD17B10KMT2AMAPTALDH1A1 | |
| SCHEMBL7792320 | 0.83 | L3MBTL1 (0.41) | HSD17B10MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL7796129 | 0.81 | CYP1A2 (0.43) | KDM4EHSD17B10KMT2AMAPTALDH1A1 | |
| SCHEMBL7795876 | 0.81 | SMN1; SMN2 (0.38) | KDM4EKMT2AHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962493-A | HYPOLIPEMIC AGENTS; ANTICHOLESTEROL AGENTS | FUJI PHOTO FILM CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| EP-0742210-A1 | 2-MERCAPTOBENZIMIDAZOLE DERIVATIVE AND ANTIHYPERLIPEMIC OR ANTIARTERIOSCLEROTIC AGENT CONTAINING THE SAME | FUJI PHOTO FILM CO., LTD. (JP) | 1996-11-13 | — | — | EP | disclosed |