Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7796231 | 0.99 | TDP1 (0.43) | HTR2CKDM4ESMN1; SMN2TDP1ADORA2A | |
| SCHEMBL7795958 | 0.99 | TDP1 (0.43) | HTR2CKDM4ESMN1; SMN2TDP1ADORA2A | |
| SCHEMBL7796421 | 0.96 | ALDH1A1 (0.45) | HTR2CKDM4ESMN1; SMN2TDP1ADORA2A | |
| SCHEMBL7792226 | 0.96 | ALDH1A1 (0.45) | HTR2CKDM4ESMN1; SMN2TDP1ADORA2A | |
| SCHEMBL7795926 | 0.95 | POLB (0.47) | HTR2CPOLBHTR2AHTR2B | |
| SCHEMBL7795918 | 0.95 | LTA4H (0.44) | HTR2CKDM4ESMN1; SMN2TDP1ADORA2A | |
| SCHEMBL7792004 | 0.95 | ALDH1A1 (0.45) | KDM4ESMN1; SMN2ADORA2AADORA1MEN1 | |
| Hydrochloric Acid SCHEMBL7792164 | 0.94 | POLB (0.46) | HTR2CPOLBHTR2AHTR2B | |
| SCHEMBL7796456 | 0.94 | LTA4H (0.44) | HTR2CKDM4ESMN1; SMN2TDP1ADORA2A | |
| SCHEMBL7796117 | 0.94 | ALDH1A1 (0.46) | HTR2CKDM4ESMN1; SMN2TDP1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906268-B1 | ALKYLOXYAMINO SUBSTITUTED FLUORENONES AND THEIR USE AS PROTEIN KINASE C INHIBITORS | AVENTIS PHARMA INC (US) | 2001-11-28 | — | — | EP | disclosed |
| US-6004959-A | HYPOTENSIVE, ANTITUMOR, ANTIINFLAMMATORY AND ANTIASTHMATIC AGENTS; ANGIOGENESIS AND ALVEOLAR MACROPHAGE ACTIVATION INHIBITORS | HOECHST MARION ROUSSEL, INC. (US) | 1999-12-21 | — | — | US | disclosed |