Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | MAP2 | P11137 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 8/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7796321 | 0.80 | HDAC6 (0.50) | ALDH1A1HPGDMEN1KMT2AHDAC6 | |
| SCHEMBL1174363 | 0.80 | GAA (0.44) | GAAALDH1A1KDM4EHPGDMAP2 | |
| SCHEMBL7796483 | 0.74 | HDAC6 (0.47) | GAAMAPTLMNAHSD17B10HDAC6 | |
| SCHEMBL7787411 | 0.72 | HRH4 (0.48) | GAAALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL7787409 | 0.71 | HDAC6 (0.47) | ALDH1A1HPGDHDAC6L3MBTL1HDAC1 | |
| SCHEMBL10207566 | 0.69 | HDAC6 (0.44) | GAAALDH1A1KDM4EHPGDMAP2 | |
| SCHEMBL18092620 | 0.69 | KDM4E (0.58) | GAAALDH1A1KDM4EHPGDMAP2 | |
| SCHEMBL10207565 | 0.69 | GAA (0.43) | GAAALDH1A1KDM4EHPGDMAP2 | |
| SCHEMBL7795270 | 0.67 | HPGD (0.43) | ALDH1A1HPGDKMT2AMAPTHSD17B10 | |
| SCHEMBL10224072 | 0.67 | HDAC6 (0.44) | GAAALDH1A1KDM4EHPGDMAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010151317-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2010-12-29 | — | — | WO | disclosed |