Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RYR2 | Q92736 | 2/20 | 0.41 |
| ▸ | GPR183 | P32249 | 4/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7795811 | 0.87 | POLB (0.40) | HDAC6PRMT5WDR77HDAC1HPGD | |
| SCHEMBL7796321 | 0.85 | HDAC6 (0.50) | HDAC6HDAC1HPGDHDAC3ALDH1A1 | |
| SCHEMBL7795270 | 0.79 | HPGD (0.43) | HPGDALDH1A1L3MBTL1 | |
| SCHEMBL7796483 | 0.79 | HDAC6 (0.47) | HDAC6PRMT5WDR77HDAC1 | |
| SCHEMBL7796728 | 0.76 | HDAC1 (0.53) | HDAC6CA1CA2HDAC1HDAC3 | |
| SCHEMBL1173715 | 0.76 | HDAC6 (0.51) | HDAC6CA1CA2PRMT5WDR77 | |
| SCHEMBL7787411 | 0.74 | HRH4 (0.48) | CA1CA2HPGDALDH1A1L3MBTL1 | |
| SCHEMBL7799082 | 0.72 | HDAC6 (0.38) | HDAC6ALDH1A1 | |
| SCHEMBL7795271 | 0.72 | NPC1 (0.47) | HDAC6HDAC1HDAC3L3MBTL1HDAC8 | |
| SCHEMBL7796322 | 0.71 | GAA (0.41) | HDAC6HDAC1HPGDALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010151317-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2010-12-29 | — | — | WO | disclosed |