Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.38 |
| ▸ | CCNC | P24863 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7795811 | 0.87 | POLB (0.40) | HDAC6POLBMEN1KMT2AHPGD | |
| SCHEMBL7787409 | 0.85 | HDAC6 (0.47) | HDAC6HPGDHDAC8ALDH1A1HDAC1 | |
| SCHEMBL7796971 | 0.81 | ALDH1A1 (0.43) | HDAC6POLBKMT2AHPGDHSP90AA1 | |
| SCHEMBL7796483 | 0.81 | HDAC6 (0.47) | HDAC6SMN1; SMN2HDAC1 | |
| SCHEMBL7796728 | 0.80 | HDAC1 (0.53) | HDAC6HDAC8HDAC1HDAC3HDAC4 | |
| SCHEMBL7796322 | 0.80 | GAA (0.41) | HDAC6POLBMEN1KMT2AHPGD | |
| SCHEMBL7795270 | 0.79 | HPGD (0.43) | KMT2AHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL7796324 | 0.79 | HDAC6 (0.63) | HDAC6KMT2AHDAC8HDAC1HDAC3 | |
| SCHEMBL7787411 | 0.78 | HRH4 (0.48) | POLBMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL7796577 | 0.77 | HDAC1 (0.49) | HDAC6KMT2AHPGDMAPK1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010151317-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2010-12-29 | — | — | WO | disclosed |