SCHEMBL7796455

SCHEMBL7796455

Cc1cc(CCC(=O)O)cc(C2(C)CCCCC2)c1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP26B1 Q9NR63 4/20 0.44
CYP26A1 O43174 3/20 0.44
GLA P06280 1/20 0.42
TSHR P16473 1/20 0.42
ALOX12 P18054 1/20 0.42
NPSR1 Q6W5P4 2/20 0.41
S1PR1 P21453 3/20 0.40
RARB P10826 2/20 0.39
RARG P13631 2/20 0.39
PTGDR Q13258 1/20 0.39
PTGDR2 Q9Y5Y4 1/20 0.39
S1PR3 Q99500 1/20 0.39
THRA P10827 2/20 0.38
THRB P10828 2/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
ATM Q13315 1/20 0.38
HSD17B10 Q99714 1/20 0.38
CYP3A4 P08684 1/20 0.37
ACHE P22303 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7786447 0.86 GLA (0.44) CYP26B1CYP26A1GLATSHRALOX12
SCHEMBL7941331 0.85 GLA (0.44) CYP26B1CYP26A1GLATSHRALOX12
SCHEMBL7792145 0.83 GAA (0.45) CYP26B1CYP26A1GLATSHRALOX12
SCHEMBL7794944 0.83 THRA (0.41) CYP26B1CYP26A1NPSR1S1PR1RARB
SCHEMBL3807177 0.83 GLA (0.46) GLATSHRALOX12NPSR1S1PR1
SCHEMBL7943238 0.82 ALOX5 (0.37) GLATSHRALOX12NPSR1S1PR1
SCHEMBL11805442 0.82 GLA (0.45) CYP26B1CYP26A1GLATSHRALOX12
SCHEMBL13899790 0.81 GLA (0.49) CYP26B1CYP26A1GLATSHRALOX12
SCHEMBL2911296 0.81 GLA (0.44) GLATSHRALOX12NPSR1S1PR1
SCHEMBL7796128 0.81 CYP26B1 (0.52) CYP26B1CYP26A1RARBRARGPTGDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0823435-B1 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL CO (JP) 2001-11-21 EP disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5889095-A OXYGEN AND HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-03-30 US disclosed
EP-0823435-A2 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-11 EP disclosed