SCHEMBL7796128

SCHEMBL7796128

CC1(c2cc(CCC(=O)O)ccc2O)CCCCC1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP26B1 Q9NR63 4/20 0.52
CYP26A1 O43174 3/20 0.52
RARB P10826 2/20 0.49
RARG P13631 2/20 0.49
RARA P10276 1/20 0.47
RXRA P19793 2/20 0.47
CYP3A4 P08684 1/20 0.43
PTGDR Q13258 1/20 0.43
PTGDR2 Q9Y5Y4 1/20 0.43
PTPN11 Q06124 1/20 0.42
IAPP P10997 3/20 0.41
FFAR1 O14842 2/20 0.40
THRA P10827 1/20 0.40
THRB P10828 1/20 0.40
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
RXRB P28702 1/20 0.39
RXRG P48443 1/20 0.39
KEAP1 Q14145 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7940015 0.85 GAA (0.53) CYP26B1CYP26A1RARBRARGRARA
SCHEMBL7796541 0.84 RARA (0.53) CYP26B1CYP26A1RARBRARGRARA
SCHEMBL3809054 0.82 BACE1 (0.50) RARBRARGRARAPTGDRPTGDR2
SCHEMBL7943184 0.81 APP (0.51) CYP26B1CYP26A1RARBRARGRARA
SCHEMBL7796455 0.81 CYP26B1 (0.44) CYP26B1CYP26A1RARBRARGRARA
SCHEMBL7941331 0.80 GLA (0.44) CYP26B1CYP26A1RARBRARGRARA
SCHEMBL2913646 0.79 RARB (0.42) RARBRARGRARAPTPN11CA2
SCHEMBL8835889 0.79 TRPA1 (0.50) RARBRARGRARAPTGDRPTGDR2
SCHEMBL7792145 0.78 GAA (0.45) CYP26B1CYP26A1RARBRARGRXRA
SCHEMBL9556780 0.77 TRPV1 (0.51) CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0823435-B1 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL CO (JP) 2001-11-21 EP disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5889095-A OXYGEN AND HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-03-30 US disclosed
EP-0823435-A2 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-11 EP disclosed