Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | CES2 | O00748 | 4/20 | 0.56 |
| ▸ | CES1 | P23141 | 4/20 | 0.56 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.54 |
| ▸ | PPARG | P37231 | 7/20 | 0.54 |
| ▸ | PPARD | Q03181 | 7/20 | 0.54 |
| ▸ | PPARA | Q07869 | 7/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TLR2 | O60603 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | FABP4 | P15090 | 2/20 | 0.54 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.54 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8074587 | 1.00 | HAO1 (1.00) | HAO1KMT2AMAPTCES2CES1 | |
| SCHEMBL5468904 | 1.00 | HAO1 (1.00) | HAO1KMT2AMAPTCES2CES1 | |
| SCHEMBL5474445 | 1.00 | HAO1 (1.00) | HAO1KMT2AMAPTCES2CES1 | |
| SCHEMBL8741845 | 1.00 | HAO1 (1.00) | HAO1KMT2AMAPTCES2CES1 | |
| SCHEMBL1194076 | 0.98 | HAO1 (0.96) | HAO1KMT2AMAPTCES2CES1 | |
| SCHEMBL285014 | 0.91 | HAO1 (0.83) | HAO1KMT2AMAPTCES2CES1 | |
| SCHEMBL7796552 | 0.89 | HAO1 (0.80) | HAO1KMT2AMAPTCES2CES1 | |
| SCHEMBL18010753 | 0.89 | HAO1 (0.79) | HAO1KMT2AMAPTCES2CES1 | |
| SCHEMBL23437862 | 0.84 | HAO1 (0.71) | HAO1KMT2AMAPTCES2CES1 | |
| SCHEMBL11673566 | 0.84 | HAO1 (0.71) | HAO1KMT2AMAPTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2382044-A1 | NOVEL CATALYSTS FOR THE REACTION BETWEEN AN ISOCYANATE AND AN ALCOHOL | Bluestar Silicones France (FR) | 2011-11-02 | — | — | EP | claimed |
| US-20110257286-A1 | NOVEL CATALYSTS FOR REACTION BETWEEN AN ISOCYANATE AND AN ALCOHOL | BLUESTAR SILICONES FRANCE (FR) | 2011-10-20 | — | — | US | claimed |
| WO-2010043354-A1 | NOVEL CATALYSTS FOR THE REACTION BETWEEN AN ISOCYANATE AND AN ALCOHOL | BLUESTAR SILICONES FRANCE (FR) | 2010-04-22 | — | — | WO | claimed |
| EP-2382044-B1 | NOVEL CATALYSTS FOR THE REACTION BETWEEN AN ISOCYANATE AND AN ALCOHOL | ELKEM SILICONES FRANCE SAS (FR) | 2018-08-01 | — | — | EP | disclosed |
| US-8816036-B2 | Catalysts for reaction between an isocyanate and an alcohol | BLUESTAR SILICONES FRANCE SAS (FR) | 2014-08-26 | — | — | US | disclosed |
| EP-2382044-A1 | NOVEL CATALYSTS FOR THE REACTION BETWEEN AN ISOCYANATE AND AN ALCOHOL | Bluestar Silicones France (FR) | 2011-11-02 | — | — | EP | disclosed |
| US-20110257286-A1 | NOVEL CATALYSTS FOR REACTION BETWEEN AN ISOCYANATE AND AN ALCOHOL | BLUESTAR SILICONES FRANCE (FR) | 2011-10-20 | — | — | US | disclosed |
| WO-2010043354-A1 | NOVEL CATALYSTS FOR THE REACTION BETWEEN AN ISOCYANATE AND AN ALCOHOL | BLUESTAR SILICONES FRANCE (FR) | 2010-04-22 | — | — | WO | disclosed |
| US-20070010644-A1 | Elastomeric urethane composition | BASF CORPORATION. | 2007-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110257286-A1 | NOVEL CATALYSTS FOR REACTION BETWEEN AN ISOCYANATE AND AN ALCOHOL | ADH1C, ADH1A, IDH3A | HAO1 2687/4885KMT2A 520/4885MAPT 1167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.