Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.54 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | RORC | P51449 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6591553 | 0.80 | MEN1 (0.59) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL358199 | 0.78 | ALDH1A1 (0.65) | CYP3A4TSHRALDH1A1TDP1MEN1 | |
| SCHEMBL7691380 | 0.78 | CYP3A4 (0.65) | CYP3A4TSHRALDH1A1TDP1MEN1 | |
| SCHEMBL17740367 | 0.78 | ALDH1A1 (0.77) | TSHRALDH1A1AVPR2GPR27MEN1 | |
| SCHEMBL27782904 | 0.74 | KDM1A (0.64) | CYP3A4TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL16441842 | 0.74 | P2RX1 (0.71) | TSHRALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5221779 | 0.73 | RAB9A (0.65) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL7425270 | 0.73 | ALDH1A1 (0.54) | CYP3A4TSHRALDH1A1TDP1MEN1 | |
| SCHEMBL6591899 | 0.72 | LMNA (0.74) | CYP3A4ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14345211 | 0.72 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161412-A1 | NUCLEAR RECEPTOR ARYLATING COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000055118-A1 | NUCLEAR RECEPTOR ARYLATING COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2000-09-21 | — | — | WO | disclosed |