SCHEMBL7796878

SCHEMBL7796878

C=Cc1cccc(CC(=C)C(=O)O)c1

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.43
PTGS2 P35354 1/20 0.42
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
TP53 P04637 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
LTB4R Q15722 1/20 0.38
LTB4R2 Q9NPC1 1/20 0.38
ALDH1A1 P00352 2/20 0.38
TSHR P16473 1/20 0.38
CTBP2 P56545 3/20 0.37
MEN1 O00255 1/20 0.36
POLB P06746 1/20 0.36
KMT2A Q03164 1/20 0.36
KDM4E B2RXH2 1/20 0.36
PKM P14618 1/20 0.36
CES2 O00748 1/20 0.34
CES1 P23141 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1515936 0.84 AKR1B1 (0.52) FAAHPTGS2TP53TDP1ALDH1A1
SCHEMBL3371585 0.84 FAAH (0.41) FAAHPTGS2CYP3A4CYP2C9TP53
SCHEMBL3423556 0.84 CTBP2 (0.44) CTBP2CES2CES1
SCHEMBL3624135 0.83 FAAH (0.42) FAAHPTGS2CYP3A4CYP2C9TP53
Hydrochloric Acid SCHEMBL3624137 0.83 AKR1B1 (0.50) FAAHPTGS2TP53TDP1LTB4R
SCHEMBL23365340 0.79 TP53 (0.46) FAAHPTGS2CYP3A4CYP2C9TP53
SCHEMBL3816810 0.79 ALDH1A1 (0.42) CYP3A4CYP2C9TDP1ALDH1A1TSHR
SCHEMBL1137221 0.77 CTBP2 (0.60) CYP3A4CTBP2KMT2AKDM4EPKM
SCHEMBL11252367 0.76 CTBP2 (0.63) ALDH1A1CTBP2MEN1KMT2A
SCHEMBL8692259 0.76 SLC1A1 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0944656-B1 PROCESS FOR PREPARING RUBBER-MODIFIED MOULDING COMPOUNDS BASF AG (DE) 2001-07-11 EP claimed
EP-0944656-B1 PROCESS FOR PREPARING RUBBER-MODIFIED MOULDING COMPOUNDS BASF AG (DE) 2001-07-11 EP disclosed