Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PTPRB | P23467 | 1/20 | 0.39 |
| ▸ | CDC25A | P30304 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | PTEN | P60484 | 1/20 | 0.39 |
| ▸ | PTPMT1 | Q8WUK0 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20725124 | 0.85 | KEAP1 (0.55) | FAAHPTPRBCDC25ACDC25BPTEN | |
| SCHEMBL7796878 | 0.84 | FAAH (0.43) | FAAHPTGS2ALDH1A1TSHRCYP3A4 | |
| Styrene SCHEMBL14801675 | 0.83 | ALDH1A1 (0.50) | ALDH1A1TSHRKEAP1TDP1FFAR1 | |
| SCHEMBL316895 | 0.82 | FFAR1 (0.41) | ALDH1A1TSHRKEAP1TDP1FFAR1 | |
| SCHEMBL17975817 | 0.80 | FFAR1 (0.53) | ALDH1A1PTPRBCDC25ACDC25BPTEN | |
| SCHEMBL1137422 | 0.79 | DRD2 (0.50) | FFAR1 | |
| SCHEMBL2286187 | 0.78 | PTPRC (0.38) | ALDH1A1PTPRBCDC25ACDC25BPTEN | |
| SCHEMBL1921167 | 0.78 | CTBP2 (0.50) | ALDH1A1CYP3A4CYP2C9TDP1MAPT | |
| SCHEMBL1920986 | 0.78 | FFAR1 (0.50) | KEAP1FFAR1 | |
| SCHEMBL1919956 | 0.78 | PLAAT3 (0.54) | ALDH1A1FFAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9238715-B2 | Polymerizable composition for ophthalmic and medical use and antimicrobial composition obtained by polymerizing the polymerizable composition | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2016-01-19 | — | — | US | claimed |
| EP-0944656-B1 | PROCESS FOR PREPARING RUBBER-MODIFIED MOULDING COMPOUNDS | BASF AG (DE) | 2001-07-11 | — | — | EP | claimed |
| EP-0600269-B1 | Soft ocular lens material | MENICON CO LTD (JP) | 1998-02-04 | — | — | EP | claimed |
| EP-3121643-B1 | OPHTHALMIC LENS | MENICON CO LTD (JP) | 2020-07-22 | — | — | EP | disclosed |
| US-9622853-B2 | Polymeric composition for ocular devices | DAVE, Jagrat Natavar (IN) | 2017-04-18 | — | — | US | disclosed |
| US-9310624-B2 | Refractive-diffractive ophthalmic device and compositions useful for producing same | Jagrat Natavar DAVE (IN) | 2016-04-12 | — | — | US | disclosed |
| US-20160058552-A1 | PHAKIC LENS DEVICE WITH OPENINGS AND CONCENTRIC ANNULAR ZONES | DAVE, JAGRAT NATAVAR (IN) | 2016-03-03 | — | — | US | disclosed |
| US-9238715-B2 | Polymerizable composition for ophthalmic and medical use and antimicrobial composition obtained by polymerizing the polymerizable composition | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2016-01-19 | — | — | US | disclosed |
| US-20150359625-A1 | TORIC-DIFFRACTIVE LENS | DAVE, Jagrat Natavar (IN) | 2015-12-17 | — | — | US | disclosed |
| US-9034942-B2 | Polymer material, ophthalmic lens and contact lens | MENICON CO., LTD. (JP) | 2015-05-19 | — | — | US | disclosed |
| US-20140163133-A1 | POLYMERIZABLE COMPOSITION FOR OPHTHALMIC AND MEDICAL USE AND ANTIMICROBIAL COMPOSITION OBTAINED BY POLYMERIZING THE POLYMERIZABLE COMPOSITION | MENICON CO., LTD (JP) | 2014-06-12 | — | — | US | disclosed |
| EP-1750157-A1 | CONTACT LENS | MENICON CO., LTD. (JP) | 2007-02-07 | — | — | EP | disclosed |
| EP-1696257-A1 | CONTACT LENS MATERIAL | MENICON CO., LTD. (JP) | 2006-08-30 | — | — | EP | disclosed |
| US-6852795-B2 | Prepolymeric (meth)acrylates with polycyclic or aromatic segments | 3M ESPE AG (DE) | 2005-02-08 | — | — | US | disclosed |
| EP-1284979-B1 | PREPOLYMERIC (METH)ACRYLATES WITH POLYCYCLIC OR AROMATIC SEGMENTS | 3M ESPE AG (DE) | 2004-12-29 | — | — | EP | disclosed |
| US-20030166816-A1 | Prepolymeric (meth) acrylates with polycyclic or aromatic segments | 3M INNOVATIVE PROPERTIES COMPANY | 2003-09-04 | — | — | US | disclosed |
| EP-1284979-A1 | PREPOLYMERIC (METH)ACRYLATES WITH POLYCYCLIC OR AROMATIC SEGMENTS | 3M Espe AG (DE) | 2003-02-26 | — | — | EP | disclosed |
| WO-2001092271-A1 | PREPOLYMERIC (METH)ACRYLATES WITH POLYCYCLIC OR AROMATIC SEGMENTS | 3M ESPE AG (DE) | 2001-12-06 | — | — | WO | disclosed |
| EP-0944656-B1 | PROCESS FOR PREPARING RUBBER-MODIFIED MOULDING COMPOUNDS | BASF AG (DE) | 2001-07-11 | — | — | EP | disclosed |
| US-5519070-A | FLUORINE, ALKOXY POLYSILOXANE COPOLYMERS FOR INTRAOCULAR LENSES | MENICON CO., LTD. (JP) | 1996-05-21 | — | — | US | disclosed |