Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 14/20 | 0.76 |
| ▸ | MTNR1B | P49286 | 11/20 | 0.50 |
| ▸ | HTR2C | P28335 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | HTR1D | P28221 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8175004 | 1.00 | MTNR1A (0.76) | MTNR1AMTNR1BHTR2CLMNATP53 | |
| SCHEMBL8162670 | 0.88 | MTNR1A (0.75) | MTNR1AMTNR1BHTR2CLMNATP53 | |
| SCHEMBL7797256 | 0.86 | MTNR1A (1.00) | MTNR1AMTNR1BHTR2CNQO2 | |
| SCHEMBL8169118 | 0.84 | MTNR1A (0.80) | MTNR1AMTNR1BHTR2CHTR1AHTR1D | |
| SCHEMBL8162658 | 0.84 | MTNR1A (0.80) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL8173300 | 0.83 | MTNR1A (0.78) | MTNR1AMTNR1BHTR2CHTR1AHTR1D | |
| SCHEMBL8170080 | 0.83 | MTNR1A (0.78) | MTNR1AMTNR1BHTR2CHTR1AHTR1D | |
| SCHEMBL8169375 | 0.82 | MTNR1A (0.77) | MTNR1AMTNR1BHTR2CHTR1AHTR1D | |
| SCHEMBL8175008 | 0.82 | MTNR1A (0.77) | MTNR1AMTNR1BHTR2CLMNAMAPT | |
| SCHEMBL8169388 | 0.82 | MTNR1A (0.76) | MTNR1AMTNR1BHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998461-A | SLEEP DISORDERS | ADIR ET COMPAGNIE (FR) | 1999-12-07 | — | — | US | claimed |
| US-5998461-A | SLEEP DISORDERS | ADIR ET COMPAGNIE (FR) | 1999-12-07 | — | — | US | disclosed |