Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICAM1 | P05362 | 16/20 | 0.60 |
| ▸ | SELE | P16581 | 16/20 | 0.60 |
| ▸ | VCAM1 | P19320 | 7/20 | 0.60 |
| ▸ | CCNC | P24863 | 7/20 | 0.60 |
| ▸ | CDK8 | P49336 | 7/20 | 0.60 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | CDC7 | O00311 | 1/20 | 0.42 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | FLT4 | P35916 | 1/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7052567 | 0.85 | CDK8 (0.58) | ICAM1SELEVCAM1CCNCCDK8 | |
| SCHEMBL7053701 | 0.85 | ICAM1 (0.58) | ICAM1SELEVCAM1CCNCCDK8 | |
| SCHEMBL7255489 | 0.83 | ICAM1 (0.59) | ICAM1SELEVCAM1CCNCCDK8 | |
| SCHEMBL7801846 | 0.82 | CCNC (0.60) | ICAM1SELEVCAM1CCNCCDK8 | |
| SCHEMBL7931909 | 0.81 | ICAM1 (0.62) | ICAM1SELEVCAM1CCNCCDK8 | |
| SCHEMBL7797411 | 0.79 | ICAM1 (0.55) | ICAM1SELEVCAM1CCNCCDK8 | |
| SCHEMBL7671865 | 0.79 | SELE (0.57) | ICAM1SELEVCAM1CCNCCDK8 | |
| SCHEMBL7681347 | 0.78 | ICAM1 (0.55) | ICAM1SELEVCAM1CCNCCDK8 | |
| SCHEMBL7797418 | 0.78 | SELE (0.55) | ICAM1SELEVCAM1CCNCCDK8 | |
| SCHEMBL7797361 | 0.78 | ICAM1 (0.55) | ICAM1SELEVCAM1CCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010020030-A1 | Cell adhesion-inhibiting antiinflammatory compounds | ABBVIE INC. | 2001-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010020030-A1 | Cell adhesion-inhibiting antiinflammatory compounds | ICAM1, VCAM1, EPCAM | ICAM1 1/4885SELE 16/4885VCAM1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.