Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PRKCA | P17252 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15256870 | 0.89 | NPSR1 (0.47) | NPSR1TSHRPRKCAL3MBTL1PKM | |
| SCHEMBL7800500 | 0.86 | NPSR1 (0.47) | NPSR1TSHRPRKCAL3MBTL1PKM | |
| SCHEMBL7799308 | 0.85 | TSHR (0.47) | NPSR1TSHRPRKCAL3MBTL1ALDH1A1 | |
| SCHEMBL6559851 | 0.83 | NPSR1 (0.58) | NPSR1TSHRL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL17530059 | 0.82 | ALDH1A1 (0.47) | NPSR1TSHRPRKCAL3MBTL1PKM | |
| SCHEMBL23432912 | 0.81 | PKM (0.54) | NPSR1TSHRPRKCAPKMALDH1A1 | |
| SCHEMBL7799311 | 0.81 | NPSR1 (0.56) | NPSR1TSHRL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL7791073 | 0.81 | NPSR1 (0.56) | NPSR1TSHRL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL7791065 | 0.81 | TSHR (0.47) | TSHRPKMALDH1A1 | |
| SCHEMBL18315205 | 0.80 | ALDH1A1 (0.47) | NPSR1TSHRPRKCAL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1164125-A1 | ADAMANTANE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Daicel Chemical Industries, Ltd. (JP) | 2001-12-19 | — | — | EP | disclosed |