Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | VDR | P11473 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6035960 | 0.96 | HDAC1 (0.43) | PRMT5WDR77ALDH1A1LMNAPOLB | |
| SCHEMBL8651990 | 0.82 | HDAC1 (0.39) | PRMT5WDR77ALDH1A1LMNAPOLB | |
| SCHEMBL7799898 | 0.81 | PDK1 (0.39) | ALDH1A1LMNAPOLBKMT2ANPC1 | |
| SCHEMBL7797897 | 0.78 | PRMT5 (0.43) | PRMT5WDR77ALDH1A1LMNAPOLB | |
| SCHEMBL6035964 | 0.75 | PRMT5 (0.41) | PRMT5WDR77ALDH1A1LMNAPOLB | |
| SCHEMBL13816452 | 0.73 | PDK1 (0.50) | PRMT5WDR77ALDH1A1LMNAPOLB | |
| SCHEMBL7518025 | 0.72 | SMN1; SMN2 (0.71) | ALDH1A1LMNAMEN1KMT2AHPGD | |
| SCHEMBL28539247 | 0.72 | PRMT5 (0.47) | PRMT5WDR77ALDH1A1LMNAPOLB | |
| SCHEMBL8651689 | 0.72 | VDR (0.40) | PRMT5WDR77ALDH1A1LMNAPOLB | |
| SCHEMBL28550679 | 0.71 | PRMT5 (0.47) | PRMT5WDR77ALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149176-A4 | A METHOD FOR PLACING A PHOTO-CROSS-LINKING AGENT AT SPECIFIC INTERNAL SITES WITHIN THE SEQUENCE OF SYNTHETIC STRANDS OF RIBONUCLEIC ACIDS | UNIV VERMONT (US) | 2001-10-31 | — | — | EP | claimed |
| EP-1149176-A1 | A METHOD FOR PLACING A PHOTO-CROSS-LINKING AGENT AT SPECIFIC INTERNAL SITES WITHIN THE SEQUENCE OF SYNTHETIC STRANDS OF RIBONUCLEIC ACIDS | THE UNIVERSITY OF VERMONT (US) | 2001-10-31 | — | — | EP | claimed |
| US-6124099-A | Method for placing a photo-cross-linking agent at specific internal sites within the sequence of synthetic strands of ribonucleic acids | THE UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) | 2000-09-26 | — | — | US | claimed |
| WO-1999067424-A1 | A METHOD FOR PLACING A PHOTO-CROSS-LINKING AGENT AT SPECIFIC INTERNAL SITES WITHIN THE SEQUENCE OF SYNTHETIC STRANDS OF RIBONUCLEIC ACIDS | UNIVERSITY OF VERMONT (US) | 1999-12-29 | — | — | WO | claimed |
| EP-1149176-A1 | A METHOD FOR PLACING A PHOTO-CROSS-LINKING AGENT AT SPECIFIC INTERNAL SITES WITHIN THE SEQUENCE OF SYNTHETIC STRANDS OF RIBONUCLEIC ACIDS | THE UNIVERSITY OF VERMONT (US) | 2001-10-31 | — | — | EP | disclosed |
| EP-1149176-A4 | A METHOD FOR PLACING A PHOTO-CROSS-LINKING AGENT AT SPECIFIC INTERNAL SITES WITHIN THE SEQUENCE OF SYNTHETIC STRANDS OF RIBONUCLEIC ACIDS | UNIV VERMONT (US) | 2001-10-31 | — | — | EP | disclosed |
| US-6124099-A | Method for placing a photo-cross-linking agent at specific internal sites within the sequence of synthetic strands of ribonucleic acids | THE UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) | 2000-09-26 | — | — | US | disclosed |
| WO-1999067424-A1 | A METHOD FOR PLACING A PHOTO-CROSS-LINKING AGENT AT SPECIFIC INTERNAL SITES WITHIN THE SEQUENCE OF SYNTHETIC STRANDS OF RIBONUCLEIC ACIDS | UNIVERSITY OF VERMONT (US) | 1999-12-29 | — | — | WO | disclosed |