Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 8/20 | 0.39 |
| ▸ | THRB | P10828 | 3/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | THRA | P10827 | 3/20 | 0.37 |
| ▸ | VDR | P11473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6035960 | 0.86 | HDAC1 (0.43) | HDAC1THRBHDAC3HDAC4HDAC7 | |
| SCHEMBL7797894 | 0.82 | PRMT5 (0.44) | HDAC1THRBHDAC3HDAC4HDAC7 | |
| SCHEMBL6035964 | 0.74 | PRMT5 (0.41) | HDAC1THRBHDAC3HDAC4HDAC7 | |
| SCHEMBL8651994 | 0.72 | THRB (0.39) | HDAC1THRBHDAC3HDAC4HDAC7 | |
| SCHEMBL7797897 | 0.70 | PRMT5 (0.43) | THRBPRMT5WDR77ALDH1A1THRA | |
| SCHEMBL28550679 | 0.69 | PRMT5 (0.47) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL8651689 | 0.69 | VDR (0.40) | HDAC1THRBNPY5RPRMT5WDR77 | |
| SCHEMBL7799898 | 0.68 | PDK1 (0.39) | ALDH1A1LMNAPOLBMAPTKMT2A | |
| SCHEMBL28539247 | 0.68 | PRMT5 (0.47) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL13816452 | 0.67 | PDK1 (0.50) | PRMT5WDR77ALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5790627-A | Method and apparatus for observing a specimen using an X-ray microscope | RESEARCH DEVELOPMENT CORP. (JP) | 1998-08-04 | — | — | US | disclosed |