Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| P-Anisic Acid SCHEMBL7802570 | 1.00 | LTA4H (0.44) | LTA4HMAPTRAB9ANPC1ALDH1A1 | |
| P-Anisic Acid SCHEMBL7798467 | 0.97 | LTA4H (0.46) | LTA4HMAPTRAB9ANPC1ALDH1A1 | |
| P-Anisic Acid SCHEMBL7798469 | 0.97 | LTA4H (0.46) | LTA4HMAPTRAB9ANPC1ALDH1A1 | |
| P-Anisic Acid SCHEMBL7792527 | 0.92 | MAPT (0.46) | LTA4HMAPTRAB9ANPC1ALDH1A1 | |
| Ornithine SCHEMBL7801588 | 0.92 | LTA4H (0.42) | LTA4HMAPTRAB9ANPC1ALDH1A1 | |
| Ornithine SCHEMBL7792961 | 0.91 | KDM4E (0.44) | LTA4HMAPTRAB9AALDH1A1GAA | |
| Ornithine Aketoglutarate SCHEMBL7792959 | 0.91 | KDM4E (0.44) | LTA4HMAPTRAB9AALDH1A1GAA | |
| P-Anisic Acid SCHEMBL7797958 | 0.90 | LTA4H (0.49) | LTA4HMAPTRAB9AALDH1A1TDP1 | |
| P-Anisic Acid SCHEMBL7797954 | 0.90 | LTA4H (0.49) | LTA4HMAPTRAB9AALDH1A1TDP1 | |
| 4-Chloro-Benzoic Acid SCHEMBL7802644 | 0.90 | CYP2C9 (0.40) | LTA4HMAPTRAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1076649-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 2001-02-21 | — | — | EP | disclosed |
| WO-1999055679-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 1999-11-04 | — | — | WO | disclosed |