Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBFB | Q13951 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | SCD | O00767 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.46 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CSNK1A1L | Q8N752 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5500317 | 0.84 | SCD (0.54) | ALDH1A1SCDPTGS2PTGS1MAPK14 | |
| SCHEMBL5597148 | 0.84 | PTGS2 (0.50) | ALDH1A1PTGS2PTGS1MAPK14ALOX5 | |
| SCHEMBL5144240 | 0.79 | MAPK14 (0.51) | ALDH1A1SCDMAPK14ALOX5CSNK1A1 | |
| SCHEMBL6440993 | 0.79 | PTGS2 (0.52) | ALDH1A1PTGS2PTGS1MAPK14ALOX5 | |
| SCHEMBL5597237 | 0.78 | PTGS2 (0.54) | ALDH1A1SCDPTGS2PTGS1MAPK14 | |
| SCHEMBL8796678 | 0.77 | SCD (0.52) | ALDH1A1HTTKMT2ANPSR1SCD | |
| SCHEMBL6448446 | 0.77 | MAPK14 (0.64) | ALDH1A1PTGS2PTGS1MAPK14ALOX5 | |
| SCHEMBL6465182 | 0.76 | SCD (0.56) | ALDH1A1SCDPTGS2PTGS1MAPK14 | |
| SCHEMBL5501473 | 0.75 | PTGS2 (0.50) | ALDH1A1SCDPTGS2PTGS1MAPK14 | |
| SCHEMBL8885677 | 0.75 | PTGS2 (0.54) | PTGS2PTGS1MAPK14ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5700816-A | ANTIARTHRITIC AGENTS | G.D. SEARLE & CO. | 1997-12-23 | — | — | US | claimed |
| US-20010031757-A1 | Method for treating inflammatory diseases by administering a thrombin inhibitor | SHAFER JULES (US) | 2001-10-18 | — | — | US | disclosed |
| US-5700816-A | ANTIARTHRITIC AGENTS | G.D. SEARLE & CO. | 1997-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010031757-A1 | Method for treating inflammatory diseases by administering a thrombin inhibitor | PTGIS, PTMS, PTGS1 | CBFB 4320/4885ALDH1A1 2245/4885HSP90AA1 2844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.