Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 6/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | TERT | O14746 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8021769 | 0.99 | CXCR4 (0.41) | CXCR4HRH3MAOBTERTKCNH2 | |
| SCHEMBL7804098 | 0.86 | CACNA2D1 (0.36) | HRH3MAOBHTR7 | |
| Hydrochloric Acid SCHEMBL8033578 | 0.85 | CACNA2D1 (0.35) | HRH3MAOBHTR7 | |
| SCHEMBL7808743 | 0.81 | HTR1D (0.40) | HRH3HTR7 | |
| Hydrochloric Acid SCHEMBL8031140 | 0.81 | HTR1D (0.39) | HRH3HTR7 | |
| SCHEMBL7807006 | 0.78 | KMT2A (0.41) | CXCR4 | |
| SCHEMBL7807115 | 0.78 | ABCB1 (0.61) | HTR7HTR6 | |
| SCHEMBL7808727 | 0.78 | P2RX7 (0.36) | HRH3MAOBHTR7 | |
| SCHEMBL7805927 | 0.78 | HTR7 (0.50) | HTR7 | |
| Hydrochloric Acid SCHEMBL8033629 | 0.77 | KMT2A (0.40) | CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0902027-B1 | Indole and indazole derivatives, process for their preparation and the pharmaceutical compositions containing them | ADIR (FR) | 2001-07-25 | — | — | EP | disclosed |
| EP-0902027-A1 | Indole and indazole derivatives, process for their preparation and the pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-03-17 | — | — | EP | disclosed |