Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.61 |
| ▸ | HTR7 | P34969 | 8/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8032751 | 0.99 | ABCB1 (0.60) | ABCB1HTR7SIGMAR1TMEM97HTR6 | |
| SCHEMBL7805927 | 0.83 | HTR7 (0.50) | HTR7 | |
| SCHEMBL7808743 | 0.83 | HTR1D (0.40) | ABCB1HTR7SIGMAR1 | |
| SCHEMBL7804147 | 0.82 | SIGMAR1 (0.44) | ABCB1HTR7SIGMAR1TMEM97 | |
| Hydrochloric Acid SCHEMBL8021825 | 0.82 | HTR7 (0.49) | HTR7 | |
| Hydrochloric Acid SCHEMBL8031140 | 0.82 | HTR1D (0.39) | ABCB1HTR7SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8035169 | 0.82 | SIGMAR1 (0.43) | ABCB1HTR7SIGMAR1TMEM97 | |
| SCHEMBL7805912 | 0.80 | HTR1D (0.51) | SIGMAR1 | |
| SCHEMBL7806971 | 0.80 | DRD3 (0.60) | HTR7SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8031549 | 0.79 | HTR1D (0.50) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0902027-B1 | Indole and indazole derivatives, process for their preparation and the pharmaceutical compositions containing them | ADIR (FR) | 2001-07-25 | — | — | EP | disclosed |
| EP-0902027-A1 | Indole and indazole derivatives, process for their preparation and the pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-03-17 | — | — | EP | disclosed |