Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL7801470 | 0.92 | SRD5A2 (0.48) | MAOBLTA4HEPHX2MAPK14FFAR1 | |
| SCHEMBL7798437 | 0.89 | SRD5A2 (0.47) | MAOBLTA4HEPHX2MAPK14MEN1 | |
| Phenethylamine SCHEMBL7801605 | 0.88 | TAAR1 (0.53) | MAOBTAAR1 | |
| 4-Methylbenzoic Acid SCHEMBL7802556 | 0.88 | SRD5A2 (0.46) | LTA4HEPHX2MAPK14FFAR1MEN1 | |
| SCHEMBL7798600 | 0.88 | SRD5A2 (0.46) | LTA4HEPHX2MAPK14MEN1KMT2A | |
| SCHEMBL7801502 | 0.85 | TAAR1 (0.55) | MAOBTAAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL7801557 | 0.82 | MAOB (0.51) | MAOBTAAR1ALDH1A1L3MBTL1 | |
| Benzoic Acid SCHEMBL8035799 | 0.82 | TAAR1 (0.44) | MAOBTAAR1MEN1KMT2AALDH1A1 | |
| Benzoic Acid SCHEMBL7792805 | 0.81 | PPARA (0.43) | MAOBFFAR1KMT2A | |
| SCHEMBL7801541 | 0.80 | TAAR1 (0.51) | MAOBTAAR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1076649-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 2001-02-21 | — | — | EP | disclosed |
| WO-1999055679-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 1999-11-04 | — | — | WO | disclosed |