Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL7792805 | 0.89 | PPARA (0.43) | MAOBPPARGPPARDPPARAMAPT | |
| SCHEMBL7800259 | 0.89 | MAOB (0.58) | MAOBTAAR1LMNAMAPTATM | |
| 4-Methylbenzoic Acid SCHEMBL8035699 | 0.88 | MAOB (0.43) | MAOBPPARGPPARDPPARACYP1A1 | |
| SCHEMBL7801502 | 0.87 | TAAR1 (0.55) | MAOBTAAR1ALDH1A1 | |
| SCHEMBL8037475 | 0.87 | RXRA (0.44) | MAOBPPARGPPARDPPARACYP1A1 | |
| SCHEMBL7802496 | 0.86 | RXRA (0.46) | MAOBPPARGPPARDPPARAMAPT | |
| SCHEMBL7798406 | 0.82 | MAOB (0.46) | MAOBTAAR1L3MBTL1ALDH1A1 | |
| Benzoic Acid SCHEMBL7798463 | 0.81 | MAOB (0.49) | MAOBPPARACYP1A1CYP1B1SMN1; SMN2 | |
| SCHEMBL7801541 | 0.80 | TAAR1 (0.51) | MAOBTAAR1LMNAMAPT | |
| Tyramine SCHEMBL8035697 | 0.80 | TAAR1 (0.51) | MAOBTAAR1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1076649-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 2001-02-21 | — | — | EP | disclosed |
| WO-1999055679-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 1999-11-04 | — | — | WO | disclosed |