Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8811455 | 0.81 | HCAR2 (0.36) | HCAR2ALDH1A1CYP2D6CYP2C19LMNA | |
| SCHEMBL3934312 | 0.78 | TP53 (0.35) | — | |
| SCHEMBL5088264 | 0.77 | HCAR2 (0.36) | HCAR2ALDH1A1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL5088265 | 0.77 | HCAR2 (0.36) | HCAR2ALDH1A1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL3886255 | 0.74 | ALDH1A1 (0.40) | HCAR2ALDH1A1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL3886257 | 0.74 | ALDH1A1 (0.40) | HCAR2ALDH1A1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL10062279 | 0.74 | ALDH1A1 (0.40) | HCAR2ALDH1A1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL4757436 | 0.73 | ALDH1A1 (0.43) | HCAR2ALDH1A1LMNAHSD17B10PIN1 | |
| SCHEMBL15015691 | 0.73 | ALDH1A1 (0.43) | HCAR2ALDH1A1LMNAHSD17B10PIN1 | |
| SCHEMBL4757433 | 0.73 | ALDH1A1 (0.43) | HCAR2ALDH1A1LMNAHSD17B10PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0830338-B1 | Method of making 3-(aminomethyl)-5-methylhexanoic acid | WARNER LAMBERT CO (US) | 2001-12-12 | — | — | EP | disclosed |
| US-20010016665-A1 | METHOD OF MAKING (S)-3-(AMINOMETHYL) -5- METHYLHEXANOIC ACID | GROTE TODD MICHEL (US) | 2001-08-23 | — | — | US | disclosed |
| US-6046353-A | Method of making (S)-3-(aminomethyl)-5-methylhexanoic acid | WARNER-LAMBERT COMPANY (US) | 2000-04-04 | — | — | US | disclosed |
| US-5840956-A | Method of making (S)-3-(Aminomethyl)-5-Methylhexanoic acid | WARNER-LAMBERT COMPANY (US) | 1998-11-24 | — | — | US | disclosed |
| US-5637767-A | Method of making (S)-3-(aminomethyl)-5-methylhexanoic acid | WARNER-LAMBERT COMPANY (US) | 1997-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010016665-A1 | METHOD OF MAKING (S)-3-(AMINOMETHYL) -5- METHYLHEXANOIC ACID | APEH, CA6, ALKBH3 | HCAR2 170/4885ALDH1A1 316/4885CYP2D6 775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.