Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.34 |
| ▸ | FHIT | P49789 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3886257 | 1.00 | ALDH1A1 (0.40) | ALDH1A1LMNAHSD17B10GAAALOX15 | |
| SCHEMBL5088265 | 0.90 | HCAR2 (0.36) | ALDH1A1LMNAHSD17B10GAAALOX15 | |
| SCHEMBL5088264 | 0.90 | HCAR2 (0.36) | ALDH1A1LMNAHSD17B10GAAALOX15 | |
| SCHEMBL10897356 | 0.86 | ALDH1A1 (0.37) | ALDH1A1LMNAHSD17B10GAAALOX15 | |
| SCHEMBL10897365 | 0.86 | ALDH1A1 (0.37) | ALDH1A1LMNAHSD17B10GAAALOX15 | |
| SCHEMBL30831370 | 0.86 | ALDH1A1 (0.37) | ALDH1A1LMNAHSD17B10GAAALOX15 | |
| SCHEMBL10062279 | 0.82 | ALDH1A1 (0.40) | ALDH1A1LMNAHSD17B10GAAALOX15 | |
| SCHEMBL2915798 | 0.79 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10GAAALOX15 | |
| SCHEMBL16193061 | 0.78 | ALDH1A1 (0.37) | ALDH1A1LMNAHSD17B10GAAALOX15 | |
| SCHEMBL28386714 | 0.77 | ALOX15 (0.42) | ALDH1A1LMNAHSD17B10GAAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122778-A1 | PYRIDAZINONE DERIVATIVES USEFUL AS T CELL ACTIVATORS | GOSSAMER BIO SERVICES, INC. (US) | 2023-06-29 | — | — | WO | disclosed |
| US-20120142949-A1 | PROCESS FOR PREPARING PREGABALIN | HELVETICA INDUSTRIES (P) LIMITED (IN) | 2012-06-07 | — | — | US | disclosed |
| US-20120142949-A1 | PROCESS FOR PREPARING PREGABALIN | HELVETICA INDUSTRIES (P) LIMITED (IN) | 2012-06-07 | — | — | US | disclosed |
| WO-2008062460-A3 | CRYSTALLINE FORMS OF PREGABALIN | CADILA HEALTHCARE LTD (IN) | 2009-01-15 | — | — | WO | disclosed |
| WO-2008062460-A2 | CRYSTALLINE FORMS OF PREGABALIN | CADILA HEALTHCARE LIMITED (IN) | 2008-05-29 | — | — | WO | disclosed |
| WO-2008062460-A2 | CRYSTALLINE FORMS OF PREGABALIN | CADILA HEALTHCARE LIMITED (IN) | 2008-05-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142949-A1 | PROCESS FOR PREPARING PREGABALIN | GRHPR, GABRG2, GABRG1 | ALDH1A1 214/4885LMNA 1662/4885HSD17B10 55/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.