Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.44 |
| ▸ | GSR | P00390 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ornithine SCHEMBL7800241 | 0.91 | LTA4H (0.49) | ITGB3ITGA2BLMNAALDH1A1MAPT | |
| Ornithine Aketoglutarate SCHEMBL7800245 | 0.91 | LTA4H (0.49) | ITGB3ITGA2BLMNAALDH1A1MAPT | |
| Ornithine SCHEMBL7800102 | 0.91 | ALDH1A1 (0.46) | ITGB3ITGA2BLMNAALDH1A1MAPT | |
| Ornithine Aketoglutarate SCHEMBL7800104 | 0.91 | ALDH1A1 (0.46) | ITGB3ITGA2BLMNAALDH1A1MAPT | |
| Ornithine SCHEMBL7792718 | 0.88 | LTA4H (0.48) | ITGB3ITGA2BLMNAALDH1A1MAPT | |
| Ornithine Aketoglutarate SCHEMBL7792721 | 0.88 | LTA4H (0.48) | ITGB3ITGA2BLMNAALDH1A1MAPT | |
| Lysine SCHEMBL7792810 | 0.88 | LTA4H (0.48) | ITGB3ITGA2BLMNAALDH1A1MAPT | |
| Lysine SCHEMBL7792811 | 0.88 | LTA4H (0.48) | ITGB3ITGA2BLMNAALDH1A1MAPT | |
| Phenylacetic Acid SCHEMBL8025515 | 0.87 | LTA4H (0.46) | ITGB3ITGA2BLMNAALDH1A1MAPT | |
| Phenylacetic Acid SCHEMBL8025514 | 0.87 | LTA4H (0.46) | ITGB3ITGA2BLMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1076649-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 2001-02-21 | — | — | EP | disclosed |
| WO-1999055679-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 1999-11-04 | — | — | WO | disclosed |