Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7798770 | 0.99 | OPRM1 (0.41) | OPRM1OPRK1HTR7UTS2RKCNA5 | |
| SCHEMBL7799100 | 0.81 | KCNA5 (0.41) | KCNA5SCN5ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL7803104 | 0.80 | KCNA5 (0.40) | KCNA5SCN5ASIGMAR1 | |
| SCHEMBL7799084 | 0.78 | OPRM1 (0.40) | OPRM1OPRK1HTR7KCNA5SCN5A | |
| SCHEMBL8989835 | 0.78 | UTS2R (0.47) | OPRM1OPRK1HTR7UTS2R | |
| Hydrochloric Acid SCHEMBL7798767 | 0.77 | OPRM1 (0.42) | OPRM1OPRK1HTR7KCNA5SCN5A | |
| Hydrochloric Acid SCHEMBL8989821 | 0.77 | UTS2R (0.47) | OPRM1OPRK1HTR7UTS2R | |
| SCHEMBL8989847 | 0.74 | OPRM1 (0.43) | OPRM1OPRK1UTS2R | |
| SCHEMBL1762403 | 0.74 | HTR7 (0.44) | OPRM1OPRK1HTR7KCNA5SCN5A | |
| SCHEMBL1762302 | 0.74 | HTR7 (0.44) | OPRM1OPRK1HTR7KCNA5SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0720605-B1 | AMINOCYCLOHEXYLESTERS AND USES THEREOF | UNIV BRITISH COLUMBIA (CA) | 2001-12-19 | — | — | EP | claimed |