Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7803104 | 0.99 | KCNA5 (0.40) | KCNA5SCN5AAKT1PLK1ALDH1A1 | |
| SCHEMBL7799090 | 0.81 | OPRM1 (0.40) | KCNA5SCN5ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL7798770 | 0.81 | OPRM1 (0.41) | KCNA5SCN5A | |
| SCHEMBL7799084 | 0.77 | OPRM1 (0.40) | KCNA5SCN5ASIGMAR1 | |
| SCHEMBL8989833 | 0.76 | SIGMAR1 (0.38) | KCNA5SCN5AALDH1A1TSHRSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7798767 | 0.76 | OPRM1 (0.42) | KCNA5SCN5ASIGMAR1 | |
| SCHEMBL7800790 | 0.75 | HTR7 (0.39) | KCNA5SCN5APLK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7800794 | 0.75 | HTR7 (0.39) | KCNA5SCN5APLK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8989835 | 0.74 | UTS2R (0.47) | — | |
| SCHEMBL8989806 | 0.74 | SIGMAR1 (0.42) | PLK1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0720605-B1 | AMINOCYCLOHEXYLESTERS AND USES THEREOF | UNIV BRITISH COLUMBIA (CA) | 2001-12-19 | — | — | EP | claimed |