SCHEMBL7799260

SCHEMBL7799260

C=Cc1cccc([Si](C)(C)Cl)c1

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
ALDH1A1 P00352 2/20 0.39
TSHR P16473 1/20 0.39
HDAC8 Q9BY41 3/20 0.34
PTGS2 P35354 1/20 0.34
TRPA1 O75762 1/20 0.32
TGFBR1 P36897 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29434648 1.00 TP53 (0.50) TP53TDP1ALDH1A1TSHRHDAC8
SCHEMBL9715838 0.88 TP53 (0.50) TP53TDP1ALDH1A1TSHRHDAC8
SCHEMBL29434634 0.83 TP53 (0.48) TP53TDP1ALDH1A1TSHRHDAC8
SCHEMBL3157051 0.83 TP53 (0.54) TP53TDP1ALDH1A1TSHRHDAC8
SCHEMBL5702199 0.83 TP53 (0.48) TP53TDP1ALDH1A1TSHRHDAC8
SCHEMBL23493442 0.80 TP53 (0.50) TP53TDP1ALDH1A1TSHRHDAC8
SCHEMBL10621571 0.80 TP53 (0.50) TP53TDP1ALDH1A1TSHRHDAC8
SCHEMBL15473031 0.80 TP53 (0.50) TP53TDP1ALDH1A1TSHRHDAC8
SCHEMBL29434596 0.80 TP53 (0.50) TP53TDP1ALDH1A1TSHRHDAC8
SCHEMBL7865277 0.78 TP53 (0.48) TP53TDP1ALDH1A1TSHRHDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260055216-A1 Conjugated Diene-Based Polymer, Formed Body, Production Method for Conjugated Diene-Based Polymer, Rubber Composition, and Tire ASAHI KASEI KABUSHIKI KAISHA (JP) 2026-02-26 US disclosed
EP-4570827-A1 CONJUGATED DIENE-BASED POLYMER, MOLDED BODY, PRODUCTION METHOD FOR CONJUGATED DIENE-BASED POLYMER, RUBBER COMPOSITION, AND TIRE Asahi Kasei Kabushiki Kaisha (JP) 2025-06-18 EP disclosed
EP-4134382-B1 HYDROGENATED CONJUGATED DIENE-BASED POLYMER, HYDROGENATED CONJUGATED DIENE-BASED POLYMER COMPOSITION, RUBBER COMPOSITION, AND METHOD FOR PRODUCING HYDROGENATED CONJUGATED DIENE-BASED POLYMER ASAHI CHEMICAL IND (JP) 2025-05-07 EP disclosed
WO-2025028621-A1 MODIFIED CONJUGATED DIENE POLYMER, BALE, METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER, RUBBER COMPOSITION, AND TIRE 旭化成株式会社 2025-02-06 WO disclosed
US-12215179-B2 Conjugated diene-based polymer, branching agent, production method for conjugated diene-based polymer, oil extended conjugated diene-based polymer, rubber composition, and tire ASAHI KASEI KABUSHIKI KAISHA (JP) 2025-02-04 US disclosed
EP-4130050-B1 CONJUGATED DIENE POLYMER, METHOD FOR MANUFACTURING CONJUGATED DIENE POLYMER, CONJUGATED DIENE POLYMER COMPOSITION, AND RUBBER COMPOSITION ASAHI CHEMICAL IND (JP) 2024-10-09 EP disclosed
EP-4026704-B1 CONJUGATED DIENE POLYMER, METHOD FOR PRODUCING CONJUGATED DIENE POLYMER, CONJUGATED DIENE POLYMER COMPOSITION, AND RUBBER COMPOSITION ASAHI CHEMICAL IND (JP) 2024-09-04 EP disclosed
EP-4424733-A1 BLOCK COPOLYMER, ASPHALT COMPOSITION, AND MODIFIED ASPHALT MIXTURE Asahi Kasei Kabushiki Kaisha (JP) 2024-09-04 EP disclosed
EP-4421121-A1 BLOCK COPOLYMER, ASPHALT COMPOSITION, AND MODIFIED ASPHALT MIXTURE Asahi Kasei Kabushiki Kaisha (JP) 2024-08-28 EP disclosed
US-12043741-B2 Conjugated diene-based polymer composition and tire ASAHI KASEI KABUSHIKI KAISHA (JP) 2024-07-23 US disclosed
EP-0767234-A2 (Co)polymers based on vinyl monomers and their use in electroluminescent devices BAYER AG (DE) 1997-04-09 EP disclosed
US-5210143-A Block polymer of nonelastic vinyl aromatic segments. elastic diene segments and a vinyl aromatic compound having halo- or oxysilyl groups or metal halide or oxymetal groups; pressure sensitive adhesives MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-05-11 US disclosed
US-5115034-A Branching polymers with organometallic styrene derivative, a hydrocarbyl lithium initiator and a monomer MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-05-19 US disclosed
US-5098981-A POLYORGANOSILOXANE CHISSO CORPORATION (JP) 1992-03-24 US disclosed
US-5079090-A Pressure sensitive adhesives MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-01-07 US disclosed
US-4996266-A Branched elastomeric and block copolymers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-02-26 US disclosed
US-4906691-A Adhesive compositions made with condensed phase polymers and sheet materials coated therewith MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-03-06 US disclosed
EP-0349920-A2 Polyorganosiloxane Chisso Corporation (JP) 1990-01-10 EP disclosed
US-4857618-A ELASTOMERIC, ANIONIC COPOLYMERS; ORGANOMETALLIC CONDENSING AGENT; PRESSURE SENSITIVE ADHESIVES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-08-15 US disclosed
US-4857615-A Method of making condensed phase polymers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-08-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260055216-A1 Conjugated Diene-Based Polymer, Formed Body, Production Method for Conjugated Diene-Based Polymer, Rubber Composition, and Tire HMGB2, HMGB1, HMGB3 TP53 4532/4885TDP1 1360/4885ALDH1A1 2948/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.