SCHEMBL7799274

SCHEMBL7799274

CCc1c(OC)cc(OC)cc1C(N)=O

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.41
PARP15 Q460N3 3/20 0.41
PARP10 Q53GL7 2/20 0.41
SMN1; SMN2 Q16637 3/20 0.40
MAPK1 P28482 2/20 0.40
ALDH1A1 P00352 2/20 0.40
USP2 O75604 1/20 0.40
CYP3A4 P08684 1/20 0.40
HPGD P15428 1/20 0.40
RAD52 P43351 1/20 0.40
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
POLB P06746 1/20 0.39
MAPT P10636 1/20 0.39
RAB9A P51151 1/20 0.39
KMT2A Q03164 1/20 0.39
LMNA P02545 2/20 0.39
HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28975003 0.86 KDM4E (0.41) PARP10SMN1; SMN2ALDH1A1KDM4EMEN1
SCHEMBL4407605 0.85 PTPN1 (0.46) PTPN1SMN1; SMN2MAPK1ALDH1A1USP2
SCHEMBL6506991 0.81 POLB (0.41) PTPN1PARP15PARP10ALDH1A1CYP3A4
SCHEMBL27527024 0.80 KDM4E (0.42) PARP15PARP10SMN1; SMN2MAPK1ALDH1A1
SCHEMBL5185794 0.78 ALDH1A1 (0.48) PTPN1SMN1; SMN2MAPK1ALDH1A1USP2
SCHEMBL8199081 0.77 ALDH1A1 (0.45) PARP15PARP10SMN1; SMN2MAPK1ALDH1A1
SCHEMBL6465454 0.77 CYP3A4 (0.47) PARP15PARP10SMN1; SMN2MAPK1ALDH1A1
SCHEMBL9755787 0.77 KDM4E (0.42) SMN1; SMN2MAPK1ALDH1A1HPGDKDM4E
SCHEMBL27856953 0.77 KDM4E (0.45) PTPN1SMN1; SMN2MAPK1ALDH1A1USP2
SCHEMBL7792129 0.77 LCK (0.42) PTPN1PARP15SMN1; SMN2MAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1162885-A1 USE FOR CONIFER SAPLING PROTECTION Nordlander, Göran (SE) 2001-12-19 EP disclosed
WO-2000056152-A1 USE FOR CONIFER SAPLING PROTECTION ROBIGUS AB (SE) 2000-09-28 WO disclosed