Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7799274 | 0.81 | PTPN1 (0.41) | POLBALDH1A1PTPN1CYP3A4PARP15 | |
| SCHEMBL1931659 | 0.81 | POLB (0.53) | POLBALDH1A1PPARGPPARDPPARA | |
| SCHEMBL7828001 | 0.76 | CYP3A4 (0.50) | POLBALDH1A1PPARGPPARDPPARA | |
| SCHEMBL6465454 | 0.73 | CYP3A4 (0.47) | ALDH1A1CYP3A4PARP15PARP10 | |
| SCHEMBL8199081 | 0.73 | ALDH1A1 (0.45) | POLBALDH1A1CYP3A4PARP15PARP10 | |
| SCHEMBL11506306 | 0.72 | PTPN1 (0.41) | POLBALDH1A1PTGS1PTPN1CYP3A4 | |
| SCHEMBL28975003 | 0.71 | KDM4E (0.41) | POLBALDH1A1PARP10 | |
| SCHEMBL6201398 | 0.71 | PTPN1 (0.45) | ALDH1A1PTPN1CYP3A4 | |
| SCHEMBL16401724 | 0.71 | KDM4E (0.52) | POLBALDH1A1PPARAPTGS1CYP3A4 | |
| SCHEMBL30298877 | 0.71 | TNKS (0.57) | ALDH1A1PPARGPPARDPPARAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050043411-A1 | Process for preparing homophthalate derivatives | TJGEL, LLC | 2005-02-24 | — | — | US | disclosed |
| US-6797838-B2 | Process for preparing homophthalate derivatives | ILEX PRODUCTS, INC. | 2004-09-28 | — | — | US | disclosed |
| EP-1404662-A2 | PROCESS FOR PREPARING ISOCOUMARINS | Ilex Products, Inc. (US) | 2004-04-07 | — | — | EP | disclosed |
| US-20040024240-A1 | Process for preparing homophthalate derivatives | GENZYME CORPORATION | 2004-02-05 | — | — | US | disclosed |
| US-6664401-B2 | Reacting a isochroman-1,3-dione with a carbonyl compound whose carbonyl group is substituted with an acyl activating group, in the presence of a base and a solvent; use making anticancer agents for example | ILEX PRODUCTS, INC. | 2003-12-16 | — | — | US | disclosed |
| US-20030105340-A1 | Process for preparing isocoumarins | GENZYME CORPORATION | 2003-06-05 | — | — | US | disclosed |
| WO-2003004486-A2 | PROCESS FOR PREPARING ISOCOUMARINS | ILEX PRODUCTS, INC. (US) | 2003-01-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105340-A1 | Process for preparing isocoumarins | DHPS, IDH2, IDH1 | POLB 3247/4885ALDH1A1 1178/4885PPARG 2870/4885 |
| US-20050043411-A1 | Process for preparing homophthalate derivatives | HPD, HAAO, PAH | POLB 2614/4885ALDH1A1 669/4885PPARG 2750/4885 |
| US-20040024240-A1 | Process for preparing homophthalate derivatives | HPD, HAAO, PAH | POLB 2614/4885ALDH1A1 669/4885PPARG 2750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.