Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 3/20 | 0.49 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12967934 | 0.96 | GLA (0.51) | SMN1; SMN2GLATHRBTHRABACE1 | |
| SCHEMBL8944412 | 0.88 | GLA (0.50) | SMN1; SMN2GLATHRBTHRABACE1 | |
| SCHEMBL14421841 | 0.86 | MCOLN3 (0.48) | SMN1; SMN2GLATHRBTHRABACE1 | |
| SCHEMBL26930436 | 0.86 | CYP1A2 (0.52) | SMN1; SMN2GLATHRBTHRABACE1 | |
| SCHEMBL12161176 | 0.84 | MAOA (0.56) | SMN1; SMN2GLATHRBTHRABACE1 | |
| SCHEMBL12161089 | 0.84 | SMN1; SMN2 (0.46) | SMN1; SMN2GLATHRBTHRABACE1 | |
| SCHEMBL14036397 | 0.83 | SMN1; SMN2 (0.45) | SMN1; SMN2GLATHRBTHRABACE1 | |
| SCHEMBL14015795 | 0.82 | THRB (0.51) | SMN1; SMN2GLATHRBTHRAATM | |
| SCHEMBL3790208 | 0.81 | KDM4E (0.51) | SMN1; SMN2GLATHRBTHRAL3MBTL1 | |
| SCHEMBL3785500 | 0.81 | SMN1; SMN2 (0.59) | SMN1; SMN2GLATHRBTHRABACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0599886-B1 | MACROMONOMERS HAVING REACTIVE END GROUPS | MISSISSIPPI POLYMER TECH INC (US) | 2001-03-21 | — | — | EP | disclosed |
| US-5973075-A | POLYPHENYL RESINS | MAXDEM INCORPORATION (US) | 1999-10-26 | — | — | US | disclosed |
| US-5827927-A | Macromonomers having reactive end groups | MAXDEM INCORPORATED (US) | 1998-10-27 | — | — | US | disclosed |
| US-5824744-A | RIGID POLYMER RODS AND MACROMONOMERS WITH REACTIVE END GROUPS FOR REINFORCEMENT | MAXDEM INCORPORATED (US) | 1998-10-20 | — | — | US | disclosed |
| US-5670564-A | Macromonomers having reactive end groups | MAXDEM INCORPORATED (US) | 1997-09-23 | — | — | US | disclosed |