Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22138644 | 0.90 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1POLBGAANPSR1 | |
| SCHEMBL12161010 | 0.85 | SMN1; SMN2 (0.41) | SMN1; SMN2GLAESR1ALDH1A1POLB | |
| SCHEMBL12434156 | 0.85 | ESR1 (0.49) | SMN1; SMN2GLAESR1ALDH1A1GAA | |
| SCHEMBL12967934 | 0.83 | GLA (0.51) | SMN1; SMN2GLAALDH1A1NPSR1CYP1A2 | |
| SCHEMBL7799554 | 0.83 | SMN1; SMN2 (0.54) | SMN1; SMN2GLAESR1ALDH1A1POLB | |
| SCHEMBL29582108 | 0.83 | ESR1 (0.47) | SMN1; SMN2GLAESR1ALDH1A1GAA | |
| SCHEMBL17264198 | 0.81 | ESR1 (0.46) | SMN1; SMN2GLAESR1ALDH1A1GAA | |
| SCHEMBL14015795 | 0.79 | THRB (0.51) | SMN1; SMN2GLAESR1ATMRAB9A | |
| SCHEMBL11230722 | 0.79 | ESR1 (0.42) | SMN1; SMN2GLAESR1CYP1A2CYP2C9 | |
| SCHEMBL13475559 | 0.79 | ESR1 (0.49) | ESR1ALDH1A1GAANPSR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008141154-A2 | NOVEL HERBICIDE RESISTANCE GENES | DOW AGROSCIENCES LLC (US) | 2008-11-20 | — | — | WO | disclosed |