Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.39 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL7800774 | 0.93 | TAAR1 (0.50) | TAAR1KDM4EMEN1KMT2ANR4A2 | |
| SCHEMBL8035116 | 0.92 | PTGES (0.48) | TAAR1KDM4EMEN1KMT2ANR4A2 | |
| SCHEMBL7798027 | 0.92 | KDM4E (0.46) | TAAR1KDM4EMEN1KMT2ANR4A2 | |
| 4-Methylbenzoic Acid SCHEMBL8025639 | 0.89 | TAAR1 (0.42) | TAAR1KDM4ENR4A2ALDH1A1TDP1 | |
| 4-Methylbenzoic Acid SCHEMBL7792063 | 0.88 | RXRA (0.42) | TAAR1KDM4EMEN1KMT2ANR4A2 | |
| SCHEMBL7800097 | 0.88 | TAAR1 (0.61) | TAAR1KDM4EMEN1KMT2AALDH1A1 | |
| Benzoic Acid SCHEMBL7800370 | 0.87 | MEN1 (0.53) | TAAR1KDM4EMEN1KMT2ANR4A2 | |
| 4-Methylbenzoic Acid SCHEMBL7802556 | 0.86 | SRD5A2 (0.46) | MEN1KMT2ANR4A2LPAR1LPAR5 | |
| 4-Methylbenzoic Acid SCHEMBL7798453 | 0.86 | KDM4E (0.46) | TAAR1KDM4EALDH1A1TDP1 | |
| Benzoic Acid SCHEMBL8035799 | 0.83 | TAAR1 (0.44) | TAAR1KDM4EMEN1KMT2ANR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1076649-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 2001-02-21 | — | — | EP | disclosed |
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |
| WO-1999055679-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 1999-11-04 | — | — | WO | disclosed |