Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | RXRA | P19793 | 2/20 | 0.43 |
| ▸ | RXRB | P28702 | 2/20 | 0.43 |
| ▸ | RXRG | P48443 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL7800774 | 0.94 | TAAR1 (0.50) | KDM4EMEN1KMT2ATAAR1ALDH1A1 | |
| 4-Methylbenzoic Acid SCHEMBL7792499 | 0.92 | TAAR1 (0.47) | PTGESALOX5KDM4EMEN1KMT2A | |
| SCHEMBL7798027 | 0.91 | KDM4E (0.46) | KDM4EMEN1KMT2ATAAR1MAOB | |
| SCHEMBL8035858 | 0.91 | MAOB (0.46) | KDM4ETAAR1MAOBRXRARXRB | |
| Phenethylamine SCHEMBL7799179 | 0.88 | RXRA (0.52) | KDM4EMEN1KMT2ATAAR1MAOB | |
| Benzoic Acid SCHEMBL7800370 | 0.88 | MEN1 (0.53) | KDM4EMEN1KMT2ATAAR1MAOB | |
| SCHEMBL7800097 | 0.87 | TAAR1 (0.61) | KDM4EMEN1KMT2ATAAR1MAOB | |
| SCHEMBL7798405 | 0.87 | SMN1; SMN2 (0.46) | KDM4ERXRARXRBRXRGALDH1A1 | |
| SCHEMBL7798437 | 0.86 | SRD5A2 (0.47) | PTGESALOX5MEN1KMT2AMAOB | |
| Benzoic Acid SCHEMBL8035799 | 0.84 | TAAR1 (0.44) | KDM4EMEN1KMT2ATAAR1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |