Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7809738 | 0.88 | S100B (0.34) | KMT2AMEN1MAPTLMNASMN1; SMN2 | |
| SCHEMBL7807486 | 0.83 | S100B (0.36) | KMT2AMEN1MAPTLMNASMN1; SMN2 | |
| SCHEMBL7812315 | 0.82 | S100B (0.32) | KMT2AMEN1MAPTLMNASMN1; SMN2 | |
| SCHEMBL7812291 | 0.80 | ALDH1A1 (0.31) | KMT2AMEN1MAPTTDP1 | |
| SCHEMBL7807510 | 0.80 | CHRM2 (0.32) | KMT2AMEN1MAPTLMNASMN1; SMN2 | |
| SCHEMBL7809825 | 0.77 | CYP2A6 (0.37) | KMT2AMEN1MAPTLMNASMN1; SMN2 | |
| SCHEMBL7809772 | 0.77 | ADORA2A (0.39) | KMT2AMEN1MAPTLMNASMN1; SMN2 | |
| SCHEMBL7454723 | 0.76 | KMT2A (0.32) | KMT2AMEN1MAPTLMNASMN1; SMN2 | |
| SCHEMBL7807628 | 0.76 | — | — | |
| SCHEMBL7807386 | 0.75 | LOXL2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943614-B1 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | WELLA AG (DE) | 2001-12-12 | — | — | EP | disclosed |
| US-6042620-A | FOR DYEING KERATIN FIBERS SUCH AS HAIR | WELLA AG (DE) | 2000-03-28 | — | — | US | disclosed |
| EP-0943614-A2 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | Wella Aktiengesellschaft (DE) | 1999-09-22 | — | — | EP | disclosed |