Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7798540 | 0.73 | OPRM1 (0.39) | OPRM1OPRD1OPRK1HDAC1HDAC6 | |
| SCHEMBL28466070 | 0.69 | HDAC1 (0.51) | HDAC1HDAC6MEN1KMT2AL3MBTL1 | |
| SCHEMBL13434109 | 0.69 | SMN1; SMN2 (0.48) | OPRM1OPRD1OPRK1HDAC1HDAC6 | |
| SCHEMBL27460199 | 0.68 | MEN1 (0.42) | HDAC1HDAC6MEN1KMT2AAOC3 | |
| Bicarbonate SCHEMBL27892668 | 0.68 | TSHR (0.59) | LMNAPKMMEN1KMT2ANPC1 | |
| SCHEMBL9823156 | 0.67 | HDAC1 (0.54) | HDAC1HDAC6LMNAMEN1KMT2A | |
| SCHEMBL8577651 | 0.67 | MEN1 (0.39) | OPRM1OPRD1OPRK1LMNAPKM | |
| SCHEMBL8502790 | 0.67 | MEN1 (0.44) | OPRM1OPRD1OPRK1LMNAPKM | |
| SCHEMBL8504370 | 0.67 | AOC3 (0.42) | OPRM1OPRD1OPRK1LMNAPKM | |
| SCHEMBL3050230 | 0.66 | MEN1 (0.46) | HDAC1HDAC6LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1159260-A1 | NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000055124-A2 | NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2000-09-21 | — | — | WO | disclosed |