Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8505244 | 0.92 | ALDH1A1 (0.40) | MEN1KMT2AHTTL3MBTL1LMNA | |
| SCHEMBL8502790 | 0.80 | MEN1 (0.44) | MEN1KMT2AHTTL3MBTL1LMNA | |
| SCHEMBL7547811 | 0.77 | LMNA (0.45) | MEN1KMT2AHTTLMNAPKM | |
| SCHEMBL8502371 | 0.77 | OPRK1 (0.48) | MEN1KMT2AOPRM1OPRD1OPRK1 | |
| SCHEMBL8504370 | 0.74 | AOC3 (0.42) | MEN1KMT2AHTTL3MBTL1LMNA | |
| SCHEMBL7398172 | 0.73 | HPGD (0.54) | MEN1KMT2AHTTL3MBTL1LMNA | |
| SCHEMBL1529633 | 0.73 | KMT2A (0.54) | MEN1KMT2AHTTL3MBTL1LMNA | |
| SCHEMBL8648237 | 0.70 | AOC3 (0.43) | MEN1KMT2AHTTL3MBTL1LMNA | |
| SCHEMBL8502297 | 0.70 | AOC3 (0.43) | MEN1KMT2AHTTL3MBTL1LMNA | |
| SCHEMBL28466070 | 0.70 | HDAC1 (0.51) | MEN1KMT2AL3MBTL1LPAR1LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750648-A | HUMAN IMMUNODEFICIENCY VIRUS | G.D. SEARLE & CO. (US) | 1998-05-12 | — | — | US | disclosed |