Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.31 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.30 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7780331 | 0.86 | ALDH1A1 (0.32) | GAAALDH1A1LMNA | |
| Trifluoroacetic Acid SCHEMBL7789202 | 0.85 | ALDH1A1 (0.36) | GAAALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL7785294 | 0.78 | ALDH1A1 (0.31) | GAAALDH1A1LMNAAPPCYP2C19 | |
| SCHEMBL7787698 | 0.75 | ALDH1A1 (0.31) | GAAALDH1A1LMNA | |
| SCHEMBL7780375 | 0.75 | KMT2A (0.42) | GAAALDH1A1LMNAKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7801938 | 0.75 | CXCR2 (0.35) | GAAALDH1A1LMNAKMT2AHSD17B2 | |
| SCHEMBL7795456 | 0.74 | CXCR2 (0.35) | GAAALDH1A1LMNAPOLBCXCR2 | |
| SCHEMBL7787853 | 0.73 | KMT2A (0.38) | GAAALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL7784926 | 0.73 | KMT2A (0.38) | GAAALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL27530390 | 0.73 | KMT2A (0.36) | GAAALDH1A1LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |