Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 10/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7801279 | 0.85 | GAA (0.34) | ALDH1A1GAALMNACXCR2KMT2A | |
| Hydrochloric Acid SCHEMBL7801938 | 0.85 | CXCR2 (0.35) | ALDH1A1GAALMNACXCR2KMT2A | |
| SCHEMBL7795456 | 0.81 | CXCR2 (0.35) | ALDH1A1GAALMNACXCR2GPR35 | |
| SCHEMBL7780331 | 0.81 | ALDH1A1 (0.32) | ALDH1A1GAALMNA | |
| SCHEMBL7785088 | 0.80 | ALDH1A1 (0.41) | ALDH1A1GAALMNACXCR2KMT2A | |
| SCHEMBL7780740 | 0.80 | ALDH1A1 (0.41) | ALDH1A1GAALMNACXCR2KMT2A | |
| Hydrochloric Acid SCHEMBL7803627 | 0.79 | ALDH1A1 (0.41) | ALDH1A1GAALMNACXCR2KMT2A | |
| SCHEMBL7804313 | 0.76 | CXCR2 (0.38) | ALDH1A1GAALMNACXCR2KMT2A | |
| SCHEMBL7801445 | 0.75 | THRA (0.36) | ALDH1A1GAALMNACXCR2KMT2A | |
| SCHEMBL7789345 | 0.75 | ALDH1A1 (0.46) | ALDH1A1GAALMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |