SCHEMBL780148

SCHEMBL780148

CO[PH](=O)c1ccccc1C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.39
ACHE P22303 2/20 0.39
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
CA7 P43166 2/20 0.37
CA9 Q16790 2/20 0.37
CA12 O43570 1/20 0.35
CA4 P22748 1/20 0.35
CA14 Q9ULX7 1/20 0.35
ALDH1A1 P00352 2/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ESR1 P03372 1/20 0.32
CYP3A4 P08684 2/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C19 P33261 1/20 0.32
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL472002 0.84 BRD4 (0.36) TSHRACHECA1CA2CA9
SCHEMBL28510654 0.83 MAPT (0.40) TSHRACHECA1CA2CA7
SCHEMBL968904 0.81 TSHR (0.38) TSHRACHECA1CA2CA7
SCHEMBL57795 0.78 ALDH1A1 (0.39) ALDH1A1MEN1NPC1RAB9AKMT2A
SCHEMBL4877004 0.77 CA1 (0.52) TSHRCA1CA2CA7CA9
SCHEMBL28550187 0.77 TSHR (0.35) TSHRACHECA1CA2CA7
SCHEMBL777147 0.77 TSHR (0.35) TSHRACHECA1CA2CA7
SCHEMBL11653179 0.76 ALDH1A1 (0.46) TSHRCA1CA2CA7CA9
SCHEMBL11805356 0.76 LMNA (0.38) TSHRCA1CA2CA7CA9
SCHEMBL28056147 0.76 NFE2L2 (0.37) ACHECA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117263974-A Dialkyl phosphinic acid ammonium salt and preparation method and application thereof 江苏利思德新材料股份有限公司 2023-12-22 CN claimed
US-12100809-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2024-09-24 US disclosed
CN-117263974-A Dialkyl phosphinic acid ammonium salt and preparation method and application thereof 江苏利思德新材料股份有限公司 2023-12-22 CN disclosed
CN-116745339-A Novel thermoplastic polyesters and their synthesis 伊士曼化工公司 2023-09-12 CN disclosed
CN-116635448-A Polyester compositions comprising tetramethylcyclobutanediol with improved catalyst system comprising lithium and aluminum 伊士曼化工公司 2023-08-22 CN disclosed
CN-116635447-A Polyester compositions comprising tetramethylcyclobutanediol with improved catalyst systems comprising lithium and gallium atoms 伊士曼化工公司 2023-08-22 CN disclosed
CN-116568725-A Polyester compositions comprising tetramethylcyclobutanediol with improved catalyst systems comprising titanium and zinc atoms 伊士曼化工公司 2023-08-08 CN disclosed
US-20220149436-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2022-05-12 US disclosed
US-11283107-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2022-03-22 US disclosed
EP-3621141-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2020-03-11 EP disclosed
US-20090325065-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2009-12-31 US disclosed
EP-2012386-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE SECONDARY BATTERY Mitsubishi Chemical Corporation (JP) 2009-01-07 EP disclosed
US-20070087270-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE SOLUTION SECONDARY BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2007-04-19 US disclosed
US-7169511-B2 Nonaqueous electrolyte solution and nonaqueous electrolyte solution secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2007-01-30 US disclosed
EP-1555711-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS ELECTROLYTE SECONDARY BATTERY CONTAINING THE SAME Mitsubishi Chemical Corporation (JP) 2005-07-20 EP disclosed
US-20050014071-A1 Nonaqueous electrolyte solution and nonaqueous electrolyte solution secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2005-01-20 US disclosed
US-6096914-A Method for producing aluminum phosphinates TICONA GMBH (DE) 2000-08-01 US disclosed
US-4168267-A Phosphinylalkanoyl prolines E. R. SQUIBB & SONS, INC. (US) 1979-09-18 US disclosed
US-4119652-A HYDROGENATION CATALYSTS; COORDINATION COMPOUNDS OF IRIDIUM, RHODIUM OR RUTHENIUM WITH PHOSPHINE OR ARSINE LIGANDS; OPTICALLY ACTIVE MONSANTO COMPANY (US) 1978-10-10 US disclosed
US-3992273-A Method of preparing substituted phenyl phosphinic acids MONSANTO COMPANY (US) 1976-11-16 US disclosed