Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | STAT1 | P42224 | 1/20 | 0.52 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7801910 | 1.00 | MEN1 (0.65) | MEN1KMT2ALMNARAB9AMAPT | |
| SCHEMBL7621043 | 0.86 | PTGS2 (0.62) | MEN1KMT2ALMNARAB9AMAPT | |
| SCHEMBL7621052 | 0.86 | PTGS2 (0.62) | MEN1KMT2ALMNARAB9AMAPT | |
| SCHEMBL17890084 | 0.85 | TUBB4A (0.65) | MEN1KMT2ALMNARAB9AMAPT | |
| SCHEMBL17890087 | 0.85 | TUBB4A (0.65) | MEN1KMT2ALMNARAB9AMAPT | |
| SCHEMBL7623671 | 0.83 | MEN1 (0.67) | MEN1KMT2ALMNARAB9AMAPT | |
| SCHEMBL7623659 | 0.83 | MEN1 (0.67) | MEN1KMT2ALMNARAB9AMAPT | |
| SCHEMBL2244388 | 0.78 | NPBWR1 (0.81) | MEN1KMT2ALMNARAB9AMAPT | |
| SCHEMBL7631067 | 0.78 | MEN1 (0.59) | MEN1KMT2ALMNARAB9AMAPT | |
| SCHEMBL7631055 | 0.78 | MEN1 (0.59) | MEN1KMT2ALMNARAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0830345-B1 | STYRYL BENZIMIDAZOLE DERIVATIVES AS INHIBITORS OF SMOOTH MUSCLE CELL PROLIFERATION | AMERICAN HOME PROD (US) | 2001-09-05 | — | — | EP | claimed |
| EP-0830345-B1 | STYRYL BENZIMIDAZOLE DERIVATIVES AS INHIBITORS OF SMOOTH MUSCLE CELL PROLIFERATION | AMERICAN HOME PROD (US) | 2001-09-05 | — | — | EP | disclosed |