Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.59 |
| ▸ | HBB | P68871 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7810467 | 0.82 | KDM4E (0.59) | KDM4EALDH1A1MEN1KMT2ABRCA1 | |
| SCHEMBL15534280 | 0.81 | KDM4E (0.63) | KDM4EALDH1A1MEN1KMT2ABRCA1 | |
| SCHEMBL2556720 | 0.80 | KDM4E (0.62) | KDM4EALDH1A1MEN1KMT2ABRCA1 | |
| SCHEMBL29955553 | 0.80 | KDM4E (0.62) | KDM4EALDH1A1MEN1KMT2ABRCA1 | |
| SCHEMBL7802307 | 0.79 | HSPB1 (0.53) | KDM4EALDH1A1MEN1KMT2APOLB | |
| SCHEMBL20931739 | 0.79 | KDM4E (0.73) | KDM4EALDH1A1MEN1KMT2ABRCA1 | |
| SCHEMBL13639123 | 0.78 | KDM4E (0.64) | KDM4EALDH1A1MEN1KMT2ABRCA1 | |
| SCHEMBL5310795 | 0.78 | TLR4 (0.51) | ALDH1A1MEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL7808835 | 0.77 | KDM4E (0.60) | KDM4EALDH1A1MEN1KMT2ABRCA1 | |
| SCHEMBL22001783 | 0.75 | KDM4E (0.63) | KDM4EALDH1A1MEN1KMT2ABRCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066261-A1 | PYRIDINE DERIVATIVE AND PHARMACEUTICAL CONTAINING THE SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2001-01-10 | — | — | EP | disclosed |
| WO-1999048871-A1 | PYRIDINE DERIVATIVE AND PHARMACEUTICAL CONTAINING THE SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1999-09-30 | — | — | WO | disclosed |