Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | DPEP1 | P16444 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ornithine Aketoglutarate SCHEMBL7802612 | 1.00 | KMT2A (0.39) | KMT2AMEN1DPP4DPP8DPP7 | |
| Lysine SCHEMBL7802671 | 0.98 | DPP8 (0.39) | KMT2AMEN1DPP4DPP8DPP7 | |
| Lysine SCHEMBL7802667 | 0.98 | DPP8 (0.39) | KMT2AMEN1DPP4DPP8DPP7 | |
| Phenylacetic Acid SCHEMBL7802623 | 0.93 | CCR5 (0.38) | DPP4DPP8DPP7CCR5KDM4E | |
| Phenylacetic Acid SCHEMBL7799137 | 0.93 | CCR5 (0.38) | DPP4DPP8DPP7CCR5KDM4E | |
| Phenylacetic Acid SCHEMBL7799134 | 0.93 | CCR5 (0.38) | DPP4DPP8DPP7CCR5KDM4E | |
| Ornithine SCHEMBL7792680 | 0.91 | MEN1 (0.46) | KMT2AMEN1DPP4DPP8DPP7 | |
| Ornithine Aketoglutarate SCHEMBL7802652 | 0.91 | ENPP2 (0.42) | KMT2AMEN1NPC1RAB9AENPP2 | |
| Ornithine SCHEMBL7802654 | 0.91 | ENPP2 (0.42) | KMT2AMEN1NPC1RAB9AENPP2 | |
| Ornithine SCHEMBL7801486 | 0.90 | KDM4E (0.42) | KMT2AMEN1DPP4DPP8DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1076649-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 2001-02-21 | — | — | EP | disclosed |
| WO-1999055679-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 1999-11-04 | — | — | WO | disclosed |