Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | NPM1 | P06748 | 1/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | PTGES | O14684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL361089 | 0.92 | ALDH1A1 (0.52) | ALDH1A1PABPC1HTTCYP1A2CYP2C19 | |
| SCHEMBL30120440 | 0.92 | ALDH1A1 (0.52) | ALDH1A1PABPC1HTTCYP1A2CYP2C19 | |
| SCHEMBL197009 | 0.79 | PABPC1 (0.47) | PABPC1HTTCYP1A2CYP2C19PIK3R1 | |
| SCHEMBL29580471 | 0.79 | ALDH1A1 (0.55) | ALDH1A1CYP1A2CYP2C19PIK3R1PIK3CA | |
| SCHEMBL346120 | 0.79 | ALDH1A1 (0.55) | ALDH1A1CYP1A2CYP2C19PIK3R1PIK3CA | |
| SCHEMBL31634338 | 0.79 | PABPC1 (0.47) | PABPC1HTTCYP1A2CYP2C19PIK3R1 | |
| Ammonia Solution, Strong SCHEMBL28148393 | 0.78 | ALDH1A1 (0.53) | ALDH1A1CYP1A2CYP2C19PIK3R1PIK3CA | |
| SCHEMBL1258626 | 0.76 | PABPC1 (0.44) | PABPC1HTTCYP1A2CYP2C19NT5E | |
| SCHEMBL1641255 | 0.76 | PABPC1 (0.44) | ALDH1A1PABPC1HTTCYP1A2CYP2C19 | |
| SCHEMBL16671125 | 0.76 | PABPC1 (0.44) | ALDH1A1PABPC1HTTCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250360145-A1 | CSF-1R INHIBITORS AND USES THEREOF | MYROBALAN THERAPEUTICS INC (US) | 2025-11-27 | — | — | US | disclosed |
| US-20250326748-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | REMIX THERAPEUTICS INC (US) | 2025-10-23 | — | — | US | disclosed |
| CN-116425743-B | Benzo heterocyclic compound serving as PI3K alpha kinase inhibitor, and preparation method and application thereof | 贵州医科大学 | 2025-06-17 | — | — | CN | disclosed |
| EP-4539933-A1 | CSF-1R INHIBITORS AND USES THEREOF | Myrobalan Therapeutics, Inc. (US) | 2025-04-23 | — | — | EP | disclosed |
| CN-119790038-A | CSF-1R inhibitors and uses thereof | 迈巴制药公司 | 2025-04-08 | — | — | CN | disclosed |
| CN-119119033-A | Pyrazolopyridone compounds | 百济神州有限公司 | 2024-12-13 | — | — | CN | disclosed |
| WO-2024206989-A2 | FLT3 INHIBITORS AND METHODS OF USING THE SAME | BIOVENTURES, LLC (US) | 2024-10-03 | — | — | WO | disclosed |
| US-20240300951-A1 | Pyrazolopyridinone Compounds | BEIGENE LTD. (KY) | 2024-09-12 | — | — | US | disclosed |
| US-20240270751-A1 | Pyrazolopyridinone Compounds | BEIGENE LTD. (KY) | 2024-08-15 | — | — | US | disclosed |
| EP-4380936-A1 | PYRAZOLOPYRIDINONE COMPOUNDS | BeiGene, Ltd. (KY) | 2024-06-12 | — | — | EP | disclosed |
| WO-2009039134-A1 | ANTI-INFECTIVE PYRIMIDINES AND USES THEREOF | ABBOTT LABORATORIES (US) | 2009-03-26 | — | — | WO | disclosed |
| US-6313127-B1 | FOR THERAPY OF HYPERCHOLESTEROLEMIA OR ATHEROSCLEROSIS | ZENECA LIMITED (GB) | 2001-11-06 | — | — | US | disclosed |
| EP-0880501-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS PHARMACEUTICAL AGENTS | ZENECA LIMITED (GB) | 1998-12-02 | — | — | EP | disclosed |
| WO-1997028128-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS PHARMACEUTICAL AGENTS | ZENECA LIMITED (GB) | 1997-08-07 | — | — | WO | disclosed |
| US-4976772-A | POSTEMERGENT CONTROL OF GRASSY WEEDS | THE DOW CHEMICAL COMPANY (US) | 1990-12-11 | — | — | US | disclosed |
| US-4900354-A | CONTROLLING GRASSY WEEDS | THE DOW CHEMICAL COMPANY (US) | 1990-02-13 | — | — | US | disclosed |
| US-4803273-A | HERBICIDES | ICI AUSTRALIA LIMITED (AU) | 1989-02-07 | — | — | US | disclosed |
| US-4655819-A | Quinoxalinyloxy phenoxy proprionic acid derivatives as selective herbicides | ICI AUSTRALIA LIMITED (AU) | 1987-04-07 | — | — | US | disclosed |
| EP-0060607-B1 | 2-(2-HALO-4-(6-HALOQUINOXALIN-2-YLOXY)PHENOXY)PROPIONATES, PROCESS FOR THEIR SYNTHESIS, HERBICIDAL COMPOSITIONS CONTAINING THEM AND THEIR USE AS HERBICIDES | ICI AUSTRALIA LIMITED (AU) | 1985-08-28 | — | — | EP | disclosed |
| EP-0060607-A1 | 2-(2-halo-4-(6-haloquinoxalin-2-yloxy)phenoxy)propionates, process for their synthesis, herbicidal compositions containing them and their use as herbicides | ICI AUSTRALIA LIMITED (AU) | 1982-09-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240300951-A1 | Pyrazolopyridinone Compounds | NFATC1, CD4, PBK | ALDH1A1 1296/4885PABPC1 1281/4885HTT 4803/4885 |
| US-20250360145-A1 | CSF-1R INHIBITORS AND USES THEREOF | CSF1R, CSF3R, IL1RN | ALDH1A1 1248/4885PABPC1 3935/4885HTT 4279/4885 |
| US-20240270751-A1 | Pyrazolopyridinone Compounds | NFATC1, CD4, PBK | ALDH1A1 1296/4885PABPC1 1281/4885HTT 4803/4885 |
| US-20250326748-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | RBM17, SNRPA, SNRPA1 | ALDH1A1 3559/4885PABPC1 98/4885HTT 1075/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.